Miller C A, Hill S A, Hunt W E
Surg Neurol. 1985 Aug;24(2):173-80. doi: 10.1016/0090-3019(85)90181-8.
The authors present seven cases drawn from 620 consecutive cases over 30 years, in which previously undemonstrated (hence "de novo") intracranial aneurysms formed and ruptured at intervals of 3-20 years, after clipping of an initial aneurysm. Six patients were treated for rupture of a second aneurysm. All six had undergone successful treatment of a previous aneurysm; pre- and postoperative angiography showed not only successful clipping of the first aneurysm but also no incidence of multiple aneurysms. In no case was a major artery occluded at the time of the initial surgery. The implications as to natural history and the advisability of repeated arteriography in some patients with aneurysms are discussed.
作者报告了从30年间620例连续病例中选取的7例病例，这些病例中，在初次动脉瘤夹闭术后3至20年的间隔期内，先前未显示（因此是“新发”）的颅内动脉瘤形成并破裂。6例患者因第二次动脉瘤破裂接受治疗。所有6例患者先前的动脉瘤均得到成功治疗；术前和术后血管造影不仅显示首次动脉瘤夹闭成功，而且未发现多发动脉瘤。初次手术时均未出现主要动脉闭塞。本文讨论了这些病例对自然病史的影响以及对一些动脉瘤患者重复进行血管造影的可取性。
