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医院临床医生对常见感染开具短疗程抗生素的知识、机会及动机

Hospital Clinicians' Knowledge of and Opportunity and Motivation for Prescribing Short Antibiotic Courses for Common Infections.

作者信息

Wilcock Michael, Hearsey Dan, Slatter Mandy, Powell Neil

机构信息

Pharmacy Department, Royal Cornwall Hospitals NHS Trust, Truro TR1 3LJ, UK.

Pharmacy Department, Royal United Hospitals NHS Foundation Trust, Bath BA1 3NG, UK.

出版信息

Pharmacy (Basel). 2025 Mar 1;13(2):38. doi: 10.3390/pharmacy13020038.

Abstract

Short-course antibiotic therapies for common infections treated in hospital are supported by national guidelines. Hospital clinicians' knowledge of the course length recommendations for the management of common infections has not been fully explored. This study aims to assess doctors' knowledge of and explores their opportunity and motivation for prescribing short-course therapy. A survey was emailed to all prescribers working in adult medical specialties in two hospitals in England. The survey responses from both hospitals were pooled before analysis. One hundred and sixty-five responses were provided. Knowledge of the recommended short course lengths was high overall, except for severe community-acquired/hospital-acquired pneumonia (CAP/HAP), with only 44% of respondents opting for shorter-course therapy. The majority did not believe longer courses were more effective than shorter courses. We identified a gap in prescriber knowledge for appropriate antibiotic course lengths for severe CAP/HAP. Addressing this gap may contribute to antimicrobial stewardship efforts to reduce course lengths in line with national guidelines.

摘要

国家指南支持在医院治疗常见感染的短疗程抗生素疗法。医院临床医生对常见感染管理的疗程长度建议的了解尚未得到充分探究。本研究旨在评估医生对短疗程疗法的了解,并探究他们开具短疗程疗法的机会和动机。向英格兰两家医院从事成人医学专科工作的所有开处方者发送了一份调查问卷。在分析之前,将两家医院的调查回复汇总在一起。共收到165份回复。总体而言,除了重症社区获得性/医院获得性肺炎(CAP/HAP)外,对推荐的短疗程长度的知晓率较高,只有44%的受访者选择短疗程疗法。大多数人不认为长疗程比短疗程更有效。我们发现开处方者在重症CAP/HAP合适抗生素疗程长度方面的知识存在差距。弥补这一差距可能有助于抗菌管理工作,以按照国家指南缩短疗程。

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