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约旦初级医疗保健中精神药物处方的模式与适宜性

Patterns and Appropriateness of Psychotropic Medications Prescribing in Primary Healthcare in Jordan.

作者信息

Abdel-Qader Derar H, Saleh Alia, Albassam Abdullah, Taybeh Esra', Al Mazrouei Nadia, Al-Kubaisi Khalid Awad, Ibrahim Rana, Aljalamdeh Reham, Hamadi Salim, Jaradat Sahar, Al-Omoush Shorouq

机构信息

Faculty of Pharmacy & Medical Sciences, University of Petra, Amman 11196, Jordan.

Department of Pharmacy Practice, Faculty of Pharmacy, Kuwait University, Kuwait 12037, Kuwait.

出版信息

Pharmacy (Basel). 2025 Mar 18;13(2):44. doi: 10.3390/pharmacy13020044.

Abstract

BACKGROUND

Although psychotropic medications (PMs) have enormous adverse events and may cause serious harm if administered inappropriately, there is a scarcity of research concerning the patterns and appropriateness of prescribing these medications in primary care in Jordan. This study aimed to investigate the patterns and appropriateness of PM prescription in primary care, as well as the types and frequency of pharmacist interventions in community pharmacies.

METHODS

A prospective observational study was conducted in 16 community pharmacies across Jordan. A data reporting sheet was developed, validated, piloted to ensure its applicability, and filled out over 12 weeks (April to June 2023), covering three regions in Jordan.

RESULTS

Overall, 426 patients with 469 prescriptions containing 919 PM orders were observed. Among the PMs prescribed, 19.4% were prescribed inappropriately. Among the PMs, 78.7% were dispensed by pharmacists. The inappropriate prescription categories (n = 178) were overprescribing (45, 25.3%), underprescribing (19, 10.7%), inappropriate medication choice (39, 21.9%), inappropriate duration of medication therapy (64, 36.0%), and inappropriate medication dosage (11, 6.2%). The top therapeutic category requested was anti-epileptics (23.9%).

CONCLUSIONS

This study evaluated the prescribing patterns and appropriateness of PMs in Jordan, revealing notable instances of inappropriate PM prescriptions alongside varied and extensive pharmacist interventions.

摘要

背景

尽管精神药物(PMs)存在大量不良事件,若使用不当可能造成严重危害,但约旦针对这些药物在初级保健中的处方模式及合理性的研究却很匮乏。本研究旨在调查初级保健中PMs的处方模式及合理性,以及社区药房中药剂师干预的类型和频率。

方法

在约旦的16家社区药房开展了一项前瞻性观察研究。制定了一份数据报告表,进行了验证和预试验以确保其适用性,并在12周内(2023年4月至6月)填写完成,覆盖约旦的三个地区。

结果

总体而言,共观察到426例患者,有469张处方,包含919条PMs医嘱。在所开具的PMs中,19.4%的处方开具不当。在这些PMs中,78.7%由药剂师调配。不当处方类别(n = 178)包括处方过量(45例,25.3%)、处方不足(19例,10.7%)、药物选择不当(39例,21.9%)、药物治疗疗程不当(64例,36.0%)以及药物剂量不当(11例,6.2%)。需求最高的治疗类别是抗癫痫药(23.9%)。

结论

本研究评估了约旦PMs的处方模式及合理性,揭示了PMs不当处方的显著案例以及多样且广泛的药剂师干预情况。

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