Morozov I A, Lysikov Iu A, Khvylia S I
Tsitologiia. 1985 May;27(5):535-40.
Electron microscopic investigation of the rat small intestine revealed a great number of vesicles 50-75 nm in diameter with enterocyte microvilli. The number of vesicles increased with the increase of digestive activity in the small intestine. Vesicles were formed by gemmation of enterocyte microvilli from the lateral membrane in contraction of microvillous actin skeleton. Simultaneously with the production of exocytotic vesicles, the formation of pinocytotic vesicles in the base of microvilli was observed. There is a supposition that the vesicle gemmation is a natural process of the intestinal secretion to fulfil numerous important function: it promotes the penetration of enterocyte hydrolases into the parietal layer; equilibrates an increase in the enterocyte volume during absorption. This is a possible way of translocation of synthesized enzymes into the cytoplasm and of transport proteins on the apical surface of epithelial cells.
对大鼠小肠进行电子显微镜检查发现，有大量直径为50 - 75纳米的小泡与肠上皮细胞微绒毛相连。小泡的数量随着小肠消化活动的增强而增加。小泡是由肠上皮细胞微绒毛从侧膜出芽形成的，此时微绒毛肌动蛋白骨架发生收缩。在产生胞吐小泡的同时，还观察到在微绒毛基部形成了胞饮小泡。有一种推测认为，小泡出芽是肠道分泌的一个自然过程，以履行众多重要功能：它促进肠上皮细胞水解酶渗透到壁层；在吸收过程中平衡肠上皮细胞体积的增加。这是合成酶转运到细胞质以及上皮细胞顶端表面转运蛋白的一种可能方式。
