Wing-Lun Edwina, Marschner Simone, Quintans Desi, Taylor Sean, Troy Jakelin, Chow Clara, Zaman Sarah
Westmead Applied Research Centre, Faculty of Medicine and Health, University of Sydney, Sydney, New South Wales, Australia.
Menzies School of Health Research, Charles Darwin University, Darwin, NT, Australia.
Intern Med J. 2025 Jun;55(6):959-967. doi: 10.1111/imj.70025. Epub 2025 Mar 24.
Coronary heart disease (CHD) is the primary cause of mortality in Australia and the largest contributor to the 'gap' in cardiovascular disease deaths between Aboriginal and Torres Strait Islander (First Nations) people and non-indigenous Australians.
To assess secondary prevention of CHD in First Nations people in primary care in Australia.
Retrospective cohort study of patients with CHD under active primary care management using electronic medical records from 406 general practices across Australia. Ultimately, 50 088 people with CHD were included in the study, and 3.5% of those were First Nations people. After 5.9 years (standard deviation 5.0) in primary care adjusting for gender, age, remoteness, comorbidities, smoking status and continuity of care, First Nations peoples received equal statin (adjusted odds ratio (aOR): 0.9; 95% CI:0.8-1.1, P = 0.28), angiotensin-converting enzyme inhibitors/angiotensin II receptor antagonists (aOR:1.0; 95% CI:0.9-1.2, P = 0.85) and beta blockers (aOR:0.9;95% CI:0.8-1.1, P = 0.41) prescriptions. First Nations peoples were more likely to achieve BP <1.8 in similar proportions (35.2% vs 36.9%, P = 0.16) but less likely to have HDL-C >1.0 mmol/L (57.5% vs 73.7%, P < 0.001), triglycerides<2.0 mmol/L (61.7% vs 76.0%, P < 0.001) and HbA1C ≤ 53 mmol/mol (7.0%) (67.7% vs 82.1%, P < 0.001). A higher proportion of First Nations people had HbA1c measured (75.7% vs 66.6%, P < 0.001).
First Nations peoples with CHD under active primary care management received similar secondary prevention medications and achieved BP and LDL-C targets as frequently as non-indigenous Australians. A focus on easier access to facilitate attending primary care is needed to close the gap as well as addressing social determinants of health and structural inequities.
冠心病(CHD)是澳大利亚的主要死因,也是原住民和托雷斯海峡岛民(第一民族)与非原住民澳大利亚人在心血管疾病死亡方面“差距”的最大促成因素。
评估澳大利亚初级保健中第一民族人群冠心病的二级预防情况。
采用澳大利亚406家全科诊所的电子病历,对接受积极初级保健管理的冠心病患者进行回顾性队列研究。最终,50088名冠心病患者被纳入研究,其中3.5%为第一民族人群。在初级保健中经过5.9年(标准差5.0),对性别、年龄、偏远程度、合并症、吸烟状况和护理连续性进行调整后,第一民族人群接受他汀类药物(调整后的优势比(aOR):0.9;95%置信区间:0.8 - 1.1,P = 0.28)、血管紧张素转换酶抑制剂/血管紧张素II受体拮抗剂(aOR:1.0;95%置信区间:0.9 - 1.2,P = 0.85)和β受体阻滞剂(aOR:0.9;95%置信区间:0.8 - 1.1,P = 0.41)处方的情况相同。第一民族人群更有可能以相似比例使血压<1.8(35.2%对36.9%,P = 0.16),但高密度脂蛋白胆固醇>1.0 mmol/L的可能性较小(57.5%对73.7%,P < 0.001),甘油三酯<2.0 mmol/L的可能性较小(61.7%对76.0%,P < 0.001),糖化血红蛋白≤53 mmol/mol的可能性较小(7.0%对67.7%对82.1%,P < 0.001)。第一民族人群中糖化血红蛋白检测比例更高(75.7%对66.6%,P < 0.001)。
在积极的初级保健管理下,患有冠心病的第一民族人群接受的二级预防药物与非原住民澳大利亚人相似,且实现血压和低密度脂蛋白胆固醇目标的频率相同。需要专注于更便捷地获得初级保健服务以缩小差距,同时解决健康的社会决定因素和结构性不平等问题。