Hahad Omar, Schmitt Volker H, Baumkötter Rieke, Michal Matthias, Chalabi Julian, Schuster Alexander K, Gianicolo Emilio, Lackner Karl J, Geschke Katharina, Weinmann-Menke Julia, Konstantinides Stavros, Daiber Andreas, Wild Philipp S, Münzel Thomas
Department of Cardiology - Cardiology I, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany.
German Center for Cardiovascular Research (DZHK), partner site Rhine-Main, Mainz, Germany.
Int J Cardiol Heart Vasc. 2025 Mar 7;57:101642. doi: 10.1016/j.ijcha.2025.101642. eCollection 2025 Apr.
Environmental factors contribute to cardiovascular disease (CVD) pathogenesis. Noise annoyance is linked to adverse cardiovascular outcomes, and earplug use may mitigate noise-related health effects. This study examines associations between earplug use, noise annoyance, and CVD in a general population sample.
Cross-sectional data from 15,010 participants (35-74 years, 2007-2012) in the German Gutenberg Health Study were analyzed. Noise annoyance from various sources and earplug use during sleep were self-reported. Prevalent CVD (atrial fibrillation, coronary artery disease, myocardial infarction, stroke, chronic heart failure, peripheral artery disease, or venous thromboembolism) was determined through self-report or medical records. Logistic regression analyses with sequential adjustments evaluated associations.
Among 14,675 participants with earplug data, 713 (4.9%) reported use. Earplug users were more likely younger women with lower cardiovascular risk profiles but higher noise annoyance (90.3% vs. 78.8%). Logistic regression revealed consistent positive associations between earplug use and prevalent CVD across various noise sources, persisting after adjustments for covariates. For example, the odds ratio for earplug use and prevalent CVD, adjusted for neighborhood noise annoyance and other factors, was 1.91 (95% CI 1.39-2.59). No interaction between earplug use and noise annoyance was found.
This study provides valuable insights into the relationships between earplug use, noise annoyance, and CVD. Findings highlight the need for targeted interventions addressing noise-related cardiovascular risks and emphasize the complex dynamics of these factors in cardiovascular health.
环境因素在心血管疾病(CVD)发病机制中起作用。噪音烦恼与不良心血管结局相关,使用耳塞可能减轻与噪音相关的健康影响。本研究在一般人群样本中考察使用耳塞、噪音烦恼与心血管疾病之间的关联。
对德国古登堡健康研究中15010名参与者(年龄35 - 74岁,时间为2007 - 2012年)的横断面数据进行分析。通过自我报告获取来自各种来源的噪音烦恼以及睡眠期间使用耳塞的情况。通过自我报告或医疗记录确定心血管疾病(心房颤动、冠状动脉疾病、心肌梗死、中风、慢性心力衰竭、外周动脉疾病或静脉血栓栓塞)的患病率。采用逐步调整的逻辑回归分析评估关联。
在14675名有耳塞数据的参与者中,713人(4.9%)报告使用过耳塞。使用耳塞者更可能是心血管风险较低但噪音烦恼较高的年轻女性(90.3%对78.8%)。逻辑回归显示,在各种噪音来源中,使用耳塞与心血管疾病患病率之间存在一致的正相关,在对协变量进行调整后依然存在。例如,在调整邻里噪音烦恼和其他因素后,使用耳塞与心血管疾病患病率的比值比为1.91(95%可信区间1.39 - 2.59)。未发现使用耳塞与噪音烦恼之间存在交互作用。
本研究为使用耳塞、噪音烦恼与心血管疾病之间的关系提供了有价值的见解。研究结果凸显了针对与噪音相关的心血管风险进行有针对性干预的必要性,并强调了这些因素在心血管健康中的复杂动态关系。