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2009年至2019年间匈牙利成年哮喘流行病学——一项回顾性财务数据库分析

Epidemiology of adult asthma within the Hungarian population between 2009 and 2019 - A retrospective financial database analysis.

作者信息

Sánta B, Keglevich A, Kovács T, Engi B, Südi A, Noémi E, Tamási L

机构信息

Chiesi Hungary Kft, Hungary.

Semmelweis University, Department of Pulmonology, Hungary.

出版信息

Glob Epidemiol. 2025 Mar 6;9:100191. doi: 10.1016/j.gloepi.2025.100191. eCollection 2025 Jun.

Abstract

BACKGROUND

Asthma is the most common chronic obstructive respiratory disease and is a considerable burden on the patients, caregivers and healthcare providers. However, data on epidemiology, healthcare expenditures, inhalation medication usage and comorbidities are scarce on a country-wide level.

METHODS

A retrospective analysis was performed on the Hungarian National Health Insurance Fund's financial database. All patients who had filled at least one prescription for asthma maintenance therapy between 2009-'19 had been enrolled. Prevalence for each year was assessed, based on prescriptions filled for asthma annually. Incidence was assessed only for 2011-'19. Frequency of exacerbations and their costs were calculated.

RESULTS

Through the study period 439,977 patients filled at least one prescription for asthma maintenance therapy. The number of patients having at least one prescription in 12 months increased by 20.34 % (from 132,292 to 159,225 patients). Between 2011-'19 an average of 20,742.1 new patients used asthma maintenance medications. Between 2009 and '19 an average of 4308 patients were hospitalized due to asthma, on an average 5129 times. Healthcare expenditure on hospitalizations and outpatient treatment of asthmatics increased by 28.05 %.

CONCLUSION

Through our study period a substantial increase in patient numbers and overall expenditure was seen. Number and frequency of exacerbations however decreased over the years.

摘要

背景

哮喘是最常见的慢性阻塞性呼吸道疾病,给患者、护理人员和医疗服务提供者带来了相当大的负担。然而,在全国范围内,关于流行病学、医疗支出、吸入药物使用和合并症的数据却很匮乏。

方法

对匈牙利国家健康保险基金的财务数据库进行了回顾性分析。纳入了所有在2009年至2019年期间至少开具过一张哮喘维持治疗处方的患者。根据每年开具的哮喘处方评估每年的患病率。仅对2011年至2019年评估发病率。计算了病情加重的频率及其费用。

结果

在研究期间,439977名患者至少开具过一张哮喘维持治疗处方。12个月内至少开具过一张处方的患者数量增加了20.34%(从132292名患者增加到159225名患者)。2011年至2019年期间,平均每年有20742.1名新患者使用哮喘维持药物。2009年至2019年期间,平均每年有4308名患者因哮喘住院,平均住院5129次。哮喘患者住院和门诊治疗的医疗支出增加了28.05%。

结论

在我们的研究期间,患者数量和总支出大幅增加。然而,多年来病情加重的次数和频率有所下降。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/884c/11930725/b0e62a16f290/gr1.jpg

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