Hu Hua, Yu Shukun, Zhang Jing, Zhang Hongping
Department of Health Management and Clinical Medicine, Wuhan Polytechnic University, Wuhan, Hubei 430023, China.
Wuhan Dongxihu District Centers for Disease Control and Prevention, Dongxihu District, Wuhan, Hubei 430040, China.
IDCases. 2025 Feb 6;40:e02177. doi: 10.1016/j.idcr.2025.e02177. eCollection 2025.
Viruses are the most common organisms causing hemophagocytic lymphohistiocytosis (HLH), and enterovirus infection is the most frequently diagnosed virus infection in the newborn period. However, in recent years, there have been relatively few reports of enterovirus infection in Chinese neonates complicated by HLH. Here, we describe a female preterm infant who contracted echovirus 11 at day 4 and rapidly developed sepsis during the following three days, along with fever, lethargy, disseminated intravascular coagulation (DIC), and sepsis. She was ultimately identified as having echovirus 11 complicated by HLH. This report will contribute to increasing public awareness of the link between HLH and echo 11 infection, which can aid in early identification and treatment. We reported female preterm infant who contracted echovirus 11 at day 4 and rapidly developed sepsis during the following three days, it was the first report from central China that we are aware of.
病毒是引起噬血细胞性淋巴组织细胞增生症（HLH）最常见的病原体，而肠道病毒感染是新生儿期最常被诊断出的病毒感染。然而，近年来，中国新生儿肠道病毒感染并发HLH的报道相对较少。在此，我们描述了一名女性早产儿，其在出生第4天感染了埃可病毒11型，并在接下来的三天内迅速发展为败血症，伴有发热、嗜睡、弥散性血管内凝血（DIC）和脓毒症。她最终被确诊为埃可病毒11型感染并发HLH。本报告将有助于提高公众对HLH与埃可病毒11型感染之间联系的认识，这有助于早期识别和治疗。我们报道了一名女性早产儿在出生第4天感染了埃可病毒11型，并在接下来的三天内迅速发展为败血症，据我们所知，这是来自中国中部的首例报告。
