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高强度、高频、非聚焦超声平行束单次治疗亚洲患者面部痤疮瘢痕的疗效与安全性:一项初步研究

The Efficacy and Safety of a Single Treatment of High-Intensity, High-Frequency, Non-Focused Ultrasound Parallel Beams for Facial Acne Scars in Asian Patients: A Preliminary Study.

作者信息

Boonchoo Kanjana, Hongcharu Wichai

机构信息

Dr. Wichai Clinic, Bangkok, Thailand.

出版信息

J Cosmet Dermatol. 2025 Apr;24(4):e70134. doi: 10.1111/jocd.70134.

DOI:10.1111/jocd.70134
PMID:40132902
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11936699/
Abstract

BACKGROUND

Acne vulgaris is a common inflammatory disease that often leads to changes in skin texture. While cosmetic improvement of acne scars is achievable, complete restoration remains challenging. One promising treatment is synchronous ultrasound (US) parallel beam technology, a noninvasive device that targets the mid-dermis while preserving the epidermis. This technology induces controlled thermal injury, stimulating neo-collagenesis and neo-elastinogenesis, which contribute to the improvement of atrophic acne scars.

OBJECTIVE

To assess the efficacy and safety of high-intensity, high-frequency, non-focused US parallel beams for the treatment of facial acne scars in Asian patients.

MATERIALS AND METHODS

Fourteen subjects, aged 24-55 years, underwent a single US treatment and were evaluated for improvement in facial acne scars in a retrospective study. The follow-up period extended up to 8 months after treatment. Pre- and post-treatment photographs were assessed by a blinded dermatologist using the physician global aesthetic improvement scale (PGAIS) and the acne scar severity (ASS) scale. Scar volume was measured using the Antera 3D software. Pain perception was assessed immediately after treatment using an 11-point scale. Any safety concerns were recorded and examined.

RESULTS

Fourteen Thai subjects, with a mean age of 43 years, showed significant improvement in depression volumes (small, medium, and large) at follow-up visits compared to baseline. From PGAIS results, all treated areas showed improvement. The mean pain score was 3.94. No adverse events were reported.

CONCLUSION

Synchronous US parallel beam technology appears to be a promising and safe option for treating acne scars in Asian patients.

摘要

背景

寻常痤疮是一种常见的炎症性疾病,常导致皮肤质地改变。虽然痤疮瘢痕的美容改善是可以实现的,但完全恢复仍然具有挑战性。一种有前景的治疗方法是同步超声(US)平行光束技术,这是一种非侵入性设备,可靶向真皮中层同时保留表皮。该技术可诱导可控的热损伤,刺激新胶原蛋白生成和新弹性蛋白生成,有助于改善萎缩性痤疮瘢痕。

目的

评估高强度、高频、非聚焦超声平行光束治疗亚洲患者面部痤疮瘢痕的疗效和安全性。

材料与方法

在一项回顾性研究中,14名年龄在24至55岁之间的受试者接受了单次超声治疗,并对其面部痤疮瘢痕的改善情况进行了评估。随访期延长至治疗后8个月。由一名不知情的皮肤科医生使用医生整体美学改善量表(PGAIS)和痤疮瘢痕严重程度(ASS)量表对治疗前后的照片进行评估。使用Antera 3D软件测量瘢痕体积。治疗后立即使用11分制量表评估疼痛感知。记录并检查任何安全问题。

结果

14名泰国受试者,平均年龄43岁,随访时与基线相比,凹陷体积(小、中、大)均有显著改善。根据PGAIS结果,所有治疗区域均有改善。平均疼痛评分为3.94。未报告不良事件。

结论

同步超声平行光束技术似乎是治疗亚洲患者痤疮瘢痕的一种有前景且安全的选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bf29/11936699/eaa5b556759d/JOCD-24-e70134-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bf29/11936699/e4f133b3fa0d/JOCD-24-e70134-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bf29/11936699/f7193cc1f75e/JOCD-24-e70134-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bf29/11936699/3d035b409649/JOCD-24-e70134-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bf29/11936699/db7385a04503/JOCD-24-e70134-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bf29/11936699/eaa5b556759d/JOCD-24-e70134-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bf29/11936699/e4f133b3fa0d/JOCD-24-e70134-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bf29/11936699/f7193cc1f75e/JOCD-24-e70134-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bf29/11936699/3d035b409649/JOCD-24-e70134-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bf29/11936699/db7385a04503/JOCD-24-e70134-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bf29/11936699/eaa5b556759d/JOCD-24-e70134-g001.jpg

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本文引用的文献

1
Guidelines of care for the management of acne vulgaris.寻常痤疮治疗指南。
J Am Acad Dermatol. 2024 May;90(5):1006.e1-1006.e30. doi: 10.1016/j.jaad.2023.12.017. Epub 2024 Jan 30.
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A simple drug-delivery microneedling technique modality successfully improves linear atrophic scars.一种简单的药物递送微针技术模式成功改善了线性萎缩性瘢痕。
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Acne vulgaris and the most popular and new cosmetological treatments.寻常痤疮和最受欢迎的新型美容治疗方法。
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