Davies Sarah, Doig Emmah, Gullo Matthew, Gullo Hannah
Can J Occup Ther. 2025 Mar 26:84174251327307. doi: 10.1177/00084174251327307.
People with Parkinson's disease (PwPD) experience increasing disability due to progressive motor and non-motor symptoms. Comprehensive rehabilitation approaches are needed to maximize their daily functioning. CO-OP targets daily functioning and has established efficacy in populations with similar symptom profiles.
To explore the potential of CO-OP for PwPD, a feasibility randomized controlled trial (RCT) was conducted.
Consenting PwPD (= 20) were recruited to a parallel group, assessor masked RCT. Following baseline assessment, participants were randomized to CO-OP (20 sessions:10-weeks) or a waitlist control (WLC; 0 sessions: 10 weeks). Goal attainment, functional and cognitive status, quality of life, self-efficacy, transfer, and maintenance were measured. Data were analyzed using descriptive statistics and multiple regression analysis.
Effort (= 3.02/5) and enjoyment (= 3.15/5) ratings; homework completion (= 91%) and protocol adherence (= 82%) indicate that CO-OP is feasible. CO-OP was superior to the WLC on Canadian Occupational Performance Measure (COPM) performance (=<.001), COPM satisfaction (=<.001), and Performance Quality Rating Scale (PQRS; =<.001) but not the Goal Attainment Scale (GAS; = .123).
Addressing a critical gap in Parkinson's disease management, findings suggest that CO-OP is implementable, feasible, and potentially beneficial for PwPD. Further research is warranted to further establish efficacy.
帕金森病患者（PwPD）由于进行性运动和非运动症状而出现越来越多的功能障碍。需要综合康复方法来最大限度地提高他们的日常功能。CO-OP针对日常功能，并且在具有相似症状特征的人群中已确立疗效。
为探索CO-OP对帕金森病患者的潜力，开展了一项可行性随机对照试验（RCT）。
招募了同意参与的帕金森病患者（n = 20），进行平行组、评估者盲法的RCT。在基线评估后，参与者被随机分配到CO-OP组（20节课程：10周）或等待名单对照组（WLC；0节课程：10周）。测量目标达成情况、功能和认知状态、生活质量、自我效能、转移和维持情况。使用描述性统计和多元回归分析对数据进行分析。
努力程度（= 3.02/5）和愉悦程度（= 3.15/5）评分；家庭作业完成率（= 91%）和方案依从率（= 82%）表明CO-OP是可行的。在加拿大职业表现测量量表（COPM）表现（= <.001）、COPM满意度（= <.001）和表现质量评定量表（PQRS；= <.001）方面，CO-OP优于WLC，但在目标达成量表（GAS；= .123）上并非如此。
本研究结果填补了帕金森病管理方面的一个关键空白，表明CO-OP对帕金森病患者是可实施、可行且可能有益的。有必要进一步开展研究以进一步确定其疗效。
