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帕金森病日常职业表现的认知取向(CO-OP):随机试验结果

Cognitive Orientation to Daily Occupational Performance (CO-OP) in Parkinson's: Randomized Trial Findings.

作者信息

Davies Sarah, Doig Emmah, Gullo Matthew, Gullo Hannah

出版信息

Can J Occup Ther. 2025 Mar 26:84174251327307. doi: 10.1177/00084174251327307.

Abstract

BACKGROUND

People with Parkinson's disease (PwPD) experience increasing disability due to progressive motor and non-motor symptoms. Comprehensive rehabilitation approaches are needed to maximize their daily functioning. CO-OP targets daily functioning and has established efficacy in populations with similar symptom profiles.

PURPOSE

To explore the potential of CO-OP for PwPD, a feasibility randomized controlled trial (RCT) was conducted.

METHODS

Consenting PwPD (= 20) were recruited to a parallel group, assessor masked RCT. Following baseline assessment, participants were randomized to CO-OP (20 sessions:10-weeks) or a waitlist control (WLC; 0 sessions: 10 weeks). Goal attainment, functional and cognitive status, quality of life, self-efficacy, transfer, and maintenance were measured. Data were analyzed using descriptive statistics and multiple regression analysis.

RESULTS

Effort (= 3.02/5) and enjoyment (= 3.15/5) ratings; homework completion (= 91%) and protocol adherence (= 82%) indicate that CO-OP is feasible. CO-OP was superior to the WLC on Canadian Occupational Performance Measure (COPM) performance (=<.001), COPM satisfaction (=<.001), and Performance Quality Rating Scale (PQRS; =<.001) but not the Goal Attainment Scale (GAS; = .123).

CONCLUSIONS

Addressing a critical gap in Parkinson's disease management, findings suggest that CO-OP is implementable, feasible, and potentially beneficial for PwPD. Further research is warranted to further establish efficacy.

摘要

背景

帕金森病患者(PwPD)由于进行性运动和非运动症状而出现越来越多的功能障碍。需要综合康复方法来最大限度地提高他们的日常功能。CO-OP针对日常功能,并且在具有相似症状特征的人群中已确立疗效。

目的

为探索CO-OP对帕金森病患者的潜力,开展了一项可行性随机对照试验(RCT)。

方法

招募了同意参与的帕金森病患者(n = 20),进行平行组、评估者盲法的RCT。在基线评估后,参与者被随机分配到CO-OP组(20节课程:10周)或等待名单对照组(WLC;0节课程:10周)。测量目标达成情况、功能和认知状态、生活质量、自我效能、转移和维持情况。使用描述性统计和多元回归分析对数据进行分析。

结果

努力程度(= 3.02/5)和愉悦程度(= 3.15/5)评分;家庭作业完成率(= 91%)和方案依从率(= 82%)表明CO-OP是可行的。在加拿大职业表现测量量表(COPM)表现(= <.001)、COPM满意度(= <.001)和表现质量评定量表(PQRS;= <.001)方面,CO-OP优于WLC,但在目标达成量表(GAS;= .123)上并非如此。

结论

本研究结果填补了帕金森病管理方面的一个关键空白,表明CO-OP对帕金森病患者是可实施、可行且可能有益的。有必要进一步开展研究以进一步确定其疗效。

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