Sarker Md Safiullah
Virology Laboratory, Infectious Diseases Division, Dhaka 1212, Bangladesh.
World J Virol. 2025 Mar 25;14(1):100160. doi: 10.5501/wjv.v14.i1.100160.
Rhabdomyolysis is a severe condition characterized by the breakdown of muscle tissue leading to the release of intracellular components into the bloodstream. This condition, when associated with acute kidney injury (AKI), can result in significant morbidity and mortality, particularly in the context of coronavirus disease 2019 (COVID-19). This editorial discusses a retrospective study on patients with COVID-19 who developed rhabdomyolysis-related AKI. The study highlights that patients with rhabdomyolysis exhibited higher inflammatory markers, such as C-reactive protein, ferritin, and procalcitonin, and experienced worse clinical outcomes compared to those with other causes of AKI. The findings underscore the importance of early recognition and management of rhabdomyolysis in COVID-19 patients to improve prognosis and reduce mortality rates.
横纹肌溶解症是一种严重病症，其特征为肌肉组织分解，导致细胞内成分释放到血液中。这种病症与急性肾损伤（AKI）相关时，可导致显著的发病率和死亡率，尤其是在2019冠状病毒病（COVID-19）的背景下。这篇社论讨论了一项针对发生与横纹肌溶解症相关的急性肾损伤的COVID-19患者的回顾性研究。该研究强调，与其他急性肾损伤病因的患者相比，横纹肌溶解症患者表现出更高的炎症标志物，如C反应蛋白、铁蛋白和降钙素原，并且临床结局更差。这些发现强调了在COVID-19患者中早期识别和管理横纹肌溶解症对于改善预后和降低死亡率的重要性。
