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化脓性汗腺炎:流行病学和问题范围。

Hidradenitis suppurativa: Epidemiology and scope of the problem.

机构信息

Department of Dermatology, Roskilde Hospital, University of Copenhagen, Roskilde, Denmark.

Department of Dermatology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.

出版信息

J Am Acad Dermatol. 2015 Nov;73(5 Suppl 1):S4-7. doi: 10.1016/j.jaad.2015.07.052.

Abstract

Hidradenitis suppurativa (HS) is a chronic inflammatory disease involving painful, deep abscesses and chronic, draining sinus tracts. Because of the variable signs and symptoms displayed by patients, it remains widely unrecognized and difficult to treat, resulting in significant diagnostic delay and inconsistent treatment process. No medical specialty has successfully designated a criterion standard of treatment, resulting in variable care and unmet patient needs. Widespread causes and effects of HS are difficult to determine because the prevalence is dependent on a variety of things, including how and where data are collected, resulting in significant bias. Therefore, the task must be to assess existing studies to produce a best estimate of prevalence. In addition, the 3 types of studies available for HS (ie, self-report, registry-based, and group examination studies) must be evaluated because each offers important insights into who is impacted by this disease. The exact prevalence of HS remains unknown because of the difficulty in collecting and extrapolating data and the usefulness of studies; however, high comorbidity and disease severity is observed, resulting in increased hospital visits for patients with HS--nearly double that of other diseases. Finally, comparisons between HS and psoriasis are worth mentioning because the similarities are clear, but the severity of HS appears to be more debilitating in many aspects of life. This article will address the epidemiology of HS through current available research.

摘要

化脓性汗腺炎(HS)是一种慢性炎症性疾病,涉及疼痛、深部脓肿和慢性、引流窦道。由于患者表现出的症状和体征多种多样,因此该病仍然广泛未被识别且难以治疗,导致诊断明显延迟和治疗过程不一致。没有任何医学专业成功指定了治疗的标准,导致护理方式各不相同,无法满足患者的需求。由于 HS 的广泛病因和影响因素难以确定,因为其患病率取决于多种因素,包括数据的收集方式和地点,这导致了严重的偏差。因此,必须评估现有的研究,以对患病率做出最佳估计。此外,还必须评估 HS 可用的 3 种类型的研究(即自我报告、基于登记和群体检查研究),因为每种研究都提供了有关受这种疾病影响的人群的重要见解。由于数据收集和推断的难度以及研究的有用性,HS 的确切患病率仍然未知;但是,观察到该病的高合并症和疾病严重程度,导致 HS 患者的就诊次数增加——几乎是其他疾病的两倍。最后,值得一提的是 HS 与银屑病之间的比较,因为它们的相似之处很明显,但 HS 在许多生活方面的严重程度似乎更具致残性。本文将通过现有的研究来探讨 HS 的流行病学。

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