痤疮瘢痕对生活质量、支付意愿和时间权衡的影响：一项横断面分析。
The Impact of Acne Scarring on Quality of Life, Willingness-to-pay, and Time Trade-off: A Cross-sectional Analysis.
作者信息
De La Garza Henriette, Trepanowski Nicole, Flores Rene, Visutjindaporn Poom, Patzelt Nicole, Vashi Neelam A
机构信息
Drs. De La Garza, Trepanowski, Visutjindaporn, Patzelt, and Vashi are with the Department of Dermatology at the Boston University School of Medicine in Boston, Massachusetts.
Dr. De La Garza is also with the Department of Internal Medicine at Lahey Hospital and Medical Center in Burlington, Massachusetts.
出版信息
J Clin Aesthet Dermatol. 2025 Mar;18(3):71-73.
OBJECTIVE
We sought to evaluate the impact of the presence of acne scarring in patients with acne vulgaris on quality of life as assessed by the Dermatology Life Quality Index (DLQI) and the Cardiff Acne Disability Index (CADI); disease severity using the Investigator's Global Assessment of Acne (IGA); and health utility measures including willingness-to-pay, time trade-off, time spent on concealment, and percent of income willing to exchange for resolution of disease.
METHODS
We conducted a cross-sectional, single-institution survey.
RESULTS
In total, 94 patients with acne vulgaris participated, of which 53.2 percent had acne scarring and 46.8 percent did not. The presence of acne scarring was associated with higher DLQI, CADI, and IGA scores. Utility measures including willingness-to-pay, time trade-off, concealment time, and percent of income willing to exchange for resolution of disease were similar for participants with and without scarring. For participants with and without scarring, a greater impairment of quality of life as assessed by the DLQI was positively correlated with WTP25, percent of monthly income, IGA, and the CADI.
LIMITATIONS
As the study design was single-site and cross-sectional, and therefore results may not be generalizable.
CONCLUSION
The presence of acne scarring significantly impacts quality of life. A greater impairment of quality of life in patients with acne vulgaris correlates positively with severity of acne and some measures of health economics. Interventions to minimize or prevent acne scarring may reduce psychosocial burden of disease.
目的
我们试图评估寻常痤疮患者中痤疮瘢痕的存在对生活质量的影响，这是通过皮肤病生活质量指数（DLQI）和卡迪夫痤疮残疾指数（CADI）进行评估的；使用研究者对痤疮的整体评估（IGA）来评估疾病严重程度；以及健康效用测量，包括支付意愿、时间权衡、用于遮盖的时间，以及愿意为疾病治愈而交换的收入百分比。
方法
我们进行了一项单机构横断面调查。
结果
共有94名寻常痤疮患者参与，其中53.2%有痤疮瘢痕，46.8%没有。痤疮瘢痕的存在与更高的DLQI、CADI和IGA评分相关。包括支付意愿、时间权衡、遮盖时间以及愿意为疾病治愈而交换的收入百分比在内的效用测量，在有瘢痕和无瘢痕的参与者中相似。对于有瘢痕和无瘢痕的参与者，DLQI评估的生活质量受损程度越高，与WTP25、月收入百分比、IGA和CADI呈正相关。
局限性
由于研究设计是单中心横断面的，因此结果可能不具有普遍性。
结论
痤疮瘢痕的存在显著影响生活质量。寻常痤疮患者生活质量受损程度越高，与痤疮严重程度和一些健康经济学指标呈正相关。尽量减少或预防痤疮瘢痕的干预措施可能会减轻疾病的心理社会负担。
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