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苏格兰青少年学童的生活质量与痤疮:儿童皮肤病生活质量指数(CDLQI)和加的夫痤疮残疾指数(CADI)的应用

Quality of life and acne in Scottish adolescent schoolchildren: use of the Children's Dermatology Life Quality Index (CDLQI) and the Cardiff Acne Disability Index (CADI).

作者信息

Walker N, Lewis-Jones M S

机构信息

Department of Dermatology, Ninewells Hospital and Medical School, Dundee DD1 9SY, Scotland, UK.

出版信息

J Eur Acad Dermatol Venereol. 2006 Jan;20(1):45-50. doi: 10.1111/j.1468-3083.2005.01344.x.

Abstract

BACKGROUND

Acne vulgaris is known to adversely affect all aspects of quality of life. However, although acne is thought to occur in the majority of adolescents, there are few data currently available on the impact of acne in this age group.

OBJECTIVES

Measurement of the impairment of health-related quality of life (HRQoL) in teenage Scottish schoolchildren in a comparative study using two HRQoL questionnaires. A secondary objective was to collect data on the use and perceived efficacy of medical and over-the-counter (OTC) preparations.

STUDY DESIGN

An anonymous cross-sectional survey of 200 adolescent (15-18 years) Dundee schoolchildren was conducted by means of two self-reported questionnaires: the Children's Dermatology Life Quality Index (CDLQI) and the Cardiff Acne Disability Index (CADI). Data on demographics and therapeutic modalities and their perceived efficacy were also collected.

ANALYSIS

Statistical analysis was performed using the package Stata 7.0.

RESULTS

Self-reported acne was present in 83% of teenagers (147/178), with similar sex distribution (54% male, 46% female). The overall mean CDLQI score (max. 30) was low 1.7 {6% impairment} (CI -1 to 0), range 0-19. Nine pupils scored between 5 and 9 {17-30% impairment} suggesting moderate HRQoL impairment and three scored > 10 {> 33% impairment} indicating severe impairment. The overall mean CADI score (max. 15) of 1.9 {13% impairment}, CI 0 to 1 (range 0-15) was also low, but 12 pupils scored between 5 and 9 {33-60% impairment}, one scoring 10 + {> 67% impairment} and one scoring the maximum, 15 {100% impairment}. There was no significant difference in mean scores between the sexes in either questionnaire (P = 0.5). There was good correlation between the results from the two questionnaires (Spearman's rho = 0.62). Three-quarters (75%) had used OTC products, of which only a third (33%) felt they helped 'a lot'. Fifteen per cent were receiving prescribed treatment from their doctors of which 66% found it helpful.

CONCLUSIONS

Self-reported acne occurred in 83% (147/178) of the Scottish teenagers involved in this study, which confirms previous reports of a high prevalence of acne in teenagers. Cross-validation of the CLDQI and CADI demonstrated good correlation and both scales were easy to administer and identified 11% (16/147) of teenagers who perceive their lives to be significantly affected by their acne (8% moderately to severely, 3% severely). It is important to identify and treat such teenagers early to reduce the future socio-economic burden of their acne.

摘要

背景

寻常痤疮已知会对生活质量的各个方面产生不利影响。然而,尽管痤疮被认为在大多数青少年中都会出现,但目前关于痤疮对该年龄组影响的数据却很少。

目的

在一项比较研究中,使用两份健康相关生活质量(HRQoL)问卷来测量苏格兰青少年学童的健康相关生活质量受损情况。次要目的是收集有关医疗和非处方(OTC)制剂的使用情况及感知疗效的数据。

研究设计

通过两份自我报告问卷,即儿童皮肤病生活质量指数(CDLQI)和加的夫痤疮残疾指数(CADI),对200名邓迪青少年学童(15 - 18岁)进行了匿名横断面调查。还收集了人口统计学、治疗方式及其感知疗效的数据。

分析

使用Stata 7.0软件包进行统计分析。

结果

自我报告有痤疮的青少年占83%(147/178),性别分布相似(男性54%,女性46%)。CDLQI总体平均得分(最高30分)较低,为1.7 {6%受损}(可信区间 -1至0),范围为0 - 19。9名学生得分在5至9分之间{17 - 30%受损},表明健康相关生活质量有中度受损,3名学生得分>10分{>33%受损},表明有严重受损。CADI总体平均得分(最高15分)为1.9 {13%受损},可信区间0至1(范围0 - 15)也较低,但12名学生得分在5至9分之间{33 - 60%受损},1名学生得分10分及以上{>67%受损},1名学生得满分15分{100%受损}。两份问卷中,男女平均得分均无显著差异(P = 0.5)。两份问卷结果之间存在良好相关性(斯皮尔曼相关系数 = 0.62)。四分之三(75%)的人使用过非处方产品,其中只有三分之一(33%)觉得这些产品“很有帮助”。15%的人正在接受医生的处方治疗,其中66%的人觉得有帮助。

结论

参与本研究的苏格兰青少年中,83%(147/178)自我报告有痤疮,这证实了先前关于青少年痤疮高患病率的报道。CLDQI和CADI的交叉验证显示出良好的相关性,两个量表都易于实施,并识别出11%(16/147)认为自己的生活受到痤疮显著影响的青少年(8%为中度至重度,3%为重度)。尽早识别并治疗这些青少年对于减轻其未来痤疮的社会经济负担很重要。

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