Dalkiliç Şule, Boncuk Ulaş Sena, Avci Levent, Bozkurt Beyza Nur, Akbaş Alihan Abdullah, Sezer Vasfiye, Ünal Esra, Polat Ayşe Kristina, Aksu Semanur, Kara Genç Derya, Eryilmaz Halil Alper, Acar Türkan, Guzey Aras Yeşim, Acar Bilgehan Atilgan
Department of Neurology, Sakarya Training and Research Hospital, Sakarya, Turkey.
Independent Researcher, Dunkerque, France.
Brain Behav. 2025 Mar;15(3):e70395. doi: 10.1002/brb3.70395.
Carotid artery stenosis is the presence of 50% or more stenosis in the internal carotid artery (ICA) according to the North American Symptomatic Carotid Endarterectomy Trial (NASCET) criteria and is one of the leading etiological factors of ischemic stroke. The severity of stenosis is associated with stroke risk. The prevalence of bilateral carotid artery stenosis (BCAS) varies. This study aims to evaluate the clinical outcomes and complications associated with carotid artery stenting in patients with BCAS or occlusion in a comprehensive stroke center.
The data of patients who underwent carotid artery stenting (CAS) between January 2020 and September 2024 were scanned. The demographic data and comorbidities were noted from the patients' files. Then, the patients were divided into two groups. The first group is "bilateral 50%-99% ICA stenosis" and the second group is "one side ICA occluded contralateral side ICA ≥50% stenosis". Both groups were also listed as symptomatic and asymptomatic. Demographic and endovascular procedure data were analyzed.
A total of 82 patients were included in this study, 69 male (84.14%) and 13 female (15.85%). The mean age was 69.46 ± 7.24. Hypertension (HT) was the most common comorbid disease (69.51%). Sixty-six patients (80.50%) were symptomatic and 16 (19.50%) were asymptomatic. TIA developed in one patient in the first group. Two minor (The National Institutes of Health Stroke Scale [NIHSS] 1-3) and two major strokes developed in the second group. Only three patients (two in the first group, one in the second group) underwent postdilatation balloon angioplasty.
Endovascular treatment seems to be an acceptable strategy in comprehensive stroke centers where the possible complication risks can be well managed in this group of patients.
根据北美症状性颈动脉内膜切除术试验（NASCET）标准，颈动脉狭窄是指颈内动脉（ICA）存在50%或以上的狭窄，是缺血性卒中的主要病因之一。狭窄程度与卒中风险相关。双侧颈动脉狭窄（BCAS）的患病率各不相同。本研究旨在评估在综合卒中中心，BCAS或闭塞患者接受颈动脉支架置入术的临床结局和并发症。
扫描2020年1月至2024年9月期间接受颈动脉支架置入术（CAS）的患者数据。从患者病历中记录人口统计学数据和合并症。然后，将患者分为两组。第一组为“双侧ICA 50%-99%狭窄”，第二组为“一侧ICA闭塞对侧ICA≥50%狭窄”。两组又分为有症状和无症状。分析人口统计学和血管内手术数据。
本研究共纳入82例患者，男性69例（84.14%），女性13例（15.85%）。平均年龄为69.46±7.24岁。高血压（HT）是最常见的合并症（69.51%）。66例（80.50%）患者有症状，16例（19.50%）患者无症状。第一组有1例患者发生短暂性脑缺血发作（TIA）。第二组发生2例轻度（美国国立卫生研究院卒中量表[NIHSS]评分为1-3分）和2例重度卒中。只有3例患者（第一组2例，第二组1例）接受了球囊扩张后血管成形术。
在综合卒中中心，血管内治疗似乎是一种可接受的策略，在这类患者中可以很好地管理可能的并发症风险。
