Queiroga Luana de Lima, Kaufmann Oskar Grau, Ritti-Dias Raphael Mendes, Minanni Carlos André, Pitta Rafael Mathias, Wolosker Nelson
Programa de Pós-Graduação em Ciências da Saúde, Faculdade Israelita de Ciências de Saúde Albert Einstein, Hospital Israelita Albert Einstein, São Paulo, SP, Brazil.
Programa de Pós-Graduação em Ciências da Reabilitação, Universidade Nove Julho, São Paulo, SP, Brazil.
Einstein (Sao Paulo). 2025 Mar 24;23:eAO1128. doi: 10.31744/einstein_journal/2025AO1128. eCollection 2025.
This study evaluated the association between changes in physical activity and depression among 1,950 Brazilians. Individuals who increased their physical activity and those who decreased it were not associated with reduced depression. Conversely, being consistently active was identified as an independent and significant protective factor against depression in this population. ■ Persistently active individuals have strong independent protective factors against depression. ■ BMI (kg/m) is an independent risk factor for depression. ■ Individuals with depression at follow-up were older than those without depression. ■ Perceived stress is a strong independent risk factor for depression.
To evaluate the association between changes in physical activity and depression in 1,950 Brazilians.
This follow-up study included 1,950 Brazilians, aged ≥18 years, of both sexes, who participated in a health screening initiative between 2008 and 2022. Physical activity levels were evaluated using the International Physical Activity Questionnaire at baseline and follow-up, and groups related to changes in physical activity were created. Depression was assessed using the Beck Depression Inventory. Clinical data and behavioral profiles were also analyzed. Comparative and logistic regression models were used.
The multivariate analysis demonstrated that persistently active individuals had reduced depression (odds ratio [OR], 0.70, 95%CI= 0.55-0.91, p=0.006). Individuals who became active and those who became less active were not associated with a reduction in depression (respectively, OR= 0.81, 95%CI= 0.63-1.05, p=0.109 and OR= 1.11, 95%CI= 0.82-1.51, p=0.481).
Persistent activity was an independent, strong protective factor against depression in 1,950 Brazilians. Furthermore, becoming active or less active was not associated with depression in the same population.
本研究评估了1950名巴西人身体活动变化与抑郁症之间的关联。身体活动增加的个体和减少的个体与抑郁症减轻均无关联。相反，持续保持活跃被确定为该人群中预防抑郁症的一个独立且重要的保护因素。
■ 持续活跃的个体有强大的独立预防抑郁症的保护因素。
■ 体重指数（kg/m）是抑郁症的一个独立危险因素。
■ 随访时患有抑郁症的个体比未患抑郁症的个体年龄更大。
■ 感知到的压力是抑郁症的一个强大独立危险因素。
评估1950名巴西人身体活动变化与抑郁症之间的关联。
这项随访研究纳入了1950名年龄≥18岁的巴西男女，他们在2008年至2022年期间参与了一项健康筛查倡议。在基线和随访时使用国际身体活动问卷评估身体活动水平，并创建与身体活动变化相关的组。使用贝克抑郁量表评估抑郁症。还分析了临床数据和行为特征。使用了比较和逻辑回归模型。
多变量分析表明，持续活跃的个体抑郁症患病率降低（比值比[OR]，0.70，95%置信区间=0.55 - 0.91，p = 0.006）。身体活动增加的个体和减少的个体与抑郁症减轻均无关联（分别为，OR = 0.81，95%置信区间=0.63 - 1.05，p = 0.109和OR = 1.11，95%置信区间=0.82 - 1.51，p = 0.481）。
在1950名巴西人中，持续的身体活动是预防抑郁症的一个独立、强大的保护因素。此外，在同一人群中，身体活动增加或减少与抑郁症均无关联。
