Salmi T
Acta Neurol Scand. 1985 May;71(5):354-8. doi: 10.1111/j.1600-0404.1985.tb03212.x.
Critical flicker frequencies (CFF) were compared with the latencies of visual pattern reversal evoked potentials (VEP) in 2 groups of MS patients to evaluate the value of CFF in electrophysiological diagnostics of demyelination of the optic tract. A microprocessor-based device was constructed to obtain CFF thresholds with a 2-alternative forced-choice method. VEP latency was more frequently pathological than CFF, but CFF was abnormal in 2 optic neuritis patients with normal VEP. The frequency of pathological CFF and VEP was different in the patient group with a long history of MS compared with the new cases; in the freshly diagnosed group, CFF had a better diagnostic yield compared to the patients with a longer history.
比较了两组多发性硬化症（MS）患者的临界闪烁频率（CFF）与视觉模式反转诱发电位（VEP）的潜伏期，以评估CFF在视神经脱髓鞘电生理诊断中的价值。构建了一种基于微处理器的设备，采用二项迫选法获取CFF阈值。VEP潜伏期比CFF更常出现病理改变，但在2例VEP正常的视神经炎患者中CFF异常。与新发病例相比，MS病史较长的患者组中病理性CFF和VEP的频率不同；在新诊断组中，与病史较长的患者相比，CFF具有更好的诊断率。
