三环类抗抑郁药和奋乃静与人血浆的结合。正常人的方法学及研究结果 - Suppr

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Binding of tricyclic antidepressants and perazine to human plasma. Methodology and findings in normals.

作者信息

Brinkschulte M, Breyer-Pfaff U

出版信息

Naunyn Schmiedebergs Arch Pharmacol. 1979 Jul;308(1):1-7. doi: 10.1007/BF00499712.

DOI:10.1007/BF00499712

PMID:40137

Abstract

摘要

相似文献

Binding of tricyclic antidepressants and perazine to human plasma. Methodology and findings in normals.三环类抗抑郁药和奋乃静与人血浆的结合。正常人的方法学及研究结果

Naunyn Schmiedebergs Arch Pharmacol. 1979 Jul;308(1):1-7. doi: 10.1007/BF00499712.

[Specific binding of perazine, a piperazine side-chain phenothiazine drug, to a serum protein (author's transl)].哌嗪侧链吩噻嗪类药物奋乃静与一种血清蛋白的特异性结合（作者译）

Arzneimittelforschung. 1979;29(1):106-8.

Plasma protein binding of perazine and amitriptyline in psychiatric patients.精神病患者中奋乃静和阿米替林的血浆蛋白结合情况。

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[Determination of the binding of perazine and perazine sulfoxide to human serum albumin].[哌嗪及哌嗪亚砜与人血清白蛋白结合的测定]

Arch Pharm (Weinheim). 1980 May;313(5):443-8. doi: 10.1002/ardp.19803130508.

[Binding of perazine metabolites and phenothiazine derivatives to acid alpha 1-glycoprotein].[奋乃静代谢物和吩噻嗪衍生物与酸性α1-糖蛋白的结合]

Arzneimittelforschung. 1983;33(2):185-7.

Different effects of amitriptyline and imipramine on the pharmacokinetics and metabolism of perazine in rats.阿米替林和丙咪嗪对大鼠中奋乃静药代动力学及代谢的不同影响。

J Pharm Pharmacol. 2000 Dec;52(12):1473-81. doi: 10.1211/0022357001777685.

The contribution of alpha 1-acid glycoprotein, lipoproteins, and albumin to the plasma binding of perazine, amitriptyline, and nortriptyline in healthy man.α1-酸性糖蛋白、脂蛋白和白蛋白对健康男性体内奋乃静、阿米替林和去甲替林血浆结合的贡献。

Naunyn Schmiedebergs Arch Pharmacol. 1980 Oct;314(1):61-6. doi: 10.1007/BF00498432.

[Comparative investigations of the binding of perazine dimalonate (PDM) to human and bovine serum albumin (author's transl)].

Arch Pharm (Weinheim). 1979 Mar;312(3):205-13. doi: 10.1002/ardp.19793120306.

Gas-liquid chromotographic determination of perazine, thioridazine and thioridazine metabolites in human plasma.

J Chromatogr. 1976 May 12;120(1):123-8. doi: 10.1016/s0021-9673(01)99003-x.

Determination of perazine serum levels by gas liquid chromatography under clinical routine conditions.

J Clin Chem Clin Biochem. 1978 May;16(5):307-11. doi: 10.1515/cclm.1978.16.5.307.

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Pharmacokinetics of clozapine and its metabolites in psychiatric patients: plasma protein binding and renal clearance.氯氮平及其代谢产物在精神科患者中的药代动力学：血浆蛋白结合与肾脏清除率。

Br J Clin Pharmacol. 1998 Nov;46(5):453-9. doi: 10.1046/j.1365-2125.1998.00822.x.

Serum protein binding of nonsteroidal antiinflammatory drugs: a comparative study.非甾体抗炎药的血清蛋白结合：一项比较研究。

J Pharmacokinet Biopharm. 1997 Feb;25(1):63-77. doi: 10.1023/a:1025719827072.

The pharmacokinetics of nortriptyline in patients with chronic renal failure.慢性肾衰竭患者中去甲替林的药代动力学

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Antidepressive effect and pharmacokinetics of amitriptyline with consideration of unbound drug and 10-hydroxynortriptyline plasma levels.

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A quantitative study in the rat on the relationship between imipramine levels in brain and serum.一项关于大鼠脑内丙咪嗪水平与血清中丙咪嗪水平关系的定量研究。

Psychopharmacology (Berl). 1982;76(1):48-51. doi: 10.1007/BF00430754.

Binding of amitriptyline and nortriptyline in plasma determined from their equilibrium distributions between red cells and plasma, and between red cells and buffer solution.通过测定阿米替林和去甲替林在红细胞与血浆之间以及红细胞与缓冲溶液之间的平衡分布来确定它们在血浆中的结合情况。

Psychopharmacology (Berl). 1981;75(3):262-72. doi: 10.1007/BF00432436.

Pethidine binding in plasma: effects of methodological variables.血浆中哌替啶的结合：方法学变量的影响。

Br J Clin Pharmacol. 1984 Apr;17(4):411-5. doi: 10.1111/j.1365-2125.1984.tb02365.x.

Prediction of the volumes of distribution of basic drugs in humans based on data from animals.基于动物数据预测碱性药物在人体中的分布容积。

J Pharmacokinet Biopharm. 1984 Dec;12(6):587-96. doi: 10.1007/BF01059554.

Determination of free fractions of tricyclic antidepressants.

Naunyn Schmiedebergs Arch Pharmacol. 1984 Sep;327(3):260-5. doi: 10.1007/BF00502459.

Absolute bioavailability of imipramine: influence of food.

Psychopharmacology (Berl). 1984;83(1):104-6. doi: 10.1007/BF00427432.

本文引用的文献

[THE BINDING OF SULFONAMIDES TO PROTEIN BODIES. 4. CONCENTRATION AND TEMPERATURE DEPENDENCE IN PROTEIN BINDING].[磺胺类药物与蛋白质体的结合。4. 蛋白质结合中的浓度和温度依赖性]

Arzneimittelforschung. 1964 Oct;14:1139-46.

Interactions of drugs with proteins. I. Binding of tricyclic thymoleptics to human and bovine plasma proteins.

J Pharm Sci. 1970 Oct;59(10):1505-7. doi: 10.1002/jps.2600591033.

Plasma protein binding of tricyclic anti-depressants in man.三环类抗抑郁药在人体中的血浆蛋白结合情况。

Biochem Pharmacol. 1969 Sep;18(9):2135-43. doi: 10.1016/0006-2952(69)90318-9.

Age differences in drug binding by plasma proteins: studies on human foetuses, neonates and adults.血浆蛋白药物结合的年龄差异：对人类胎儿、新生儿和成年人的研究。

Eur J Clin Pharmacol. 1971 Sep;3(4):189-93. doi: 10.1007/BF00565004.

Plasma binding of imipramine and clinical outcome.丙咪嗪的血浆结合与临床疗效

Am J Psychiatry. 1973 Dec;130(12):1367-9. doi: 10.1176/ajp.130.12.1367.

[Enzymatic determination of total cholesterol in serum (author's transl)].血清总胆固醇的酶法测定（作者译）

Z Klin Chem Klin Biochem. 1974 Sep;12(9):403-7.

Protein binding of diphenylhydantoin and desmethylimipramine in plasma from patients with poor renal function.肾功能不全患者血浆中苯妥英钠和去甲丙咪嗪的蛋白结合情况。

N Engl J Med. 1971 Jul 29;285(5):264-7. doi: 10.1056/NEJM197107292850506.

Importance of assay specificity for plasma protein binding determinations.

J Pharmacokinet Biopharm. 1975 Dec;3(6):439-41. doi: 10.1007/BF01059475.

Measurement of plasma levels of tricylic psychoactive drugs and their metabolites by UV reflectance photometry of thin layer chromatograms.通过薄层色谱图的紫外反射光度法测量三环类精神活性药物及其代谢物的血浆水平。

Eur J Clin Pharmacol. 1976 Mar 22;09(5-6):457-65. doi: 10.1007/BF00606565.

A simple micro-assay for inorganic phosphate.一种用于无机磷酸盐的简单微量测定法。

Anal Biochem. 1976 Sep;75(1):201-10. doi: 10.1016/0003-2697(76)90071-3.

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