Kelly Courtney, Chan Rodney K, Carlsson Anders H
Oral and Maxillofacial Surgery, San Antonio Military Medical Center, San Antonio, TX 78216, USA.
US Army Burn Center, San Antonio Military Medical Center, San Antonio, TX 78216, USA.
Eur Burn J. 2025 Mar 6;6(1):13. doi: 10.3390/ebj6010013.
The gold standards for coverage of wounds that cannot be primarily closed are full thickness skin grafts (FTSGs) and split thickness skins graft (STSGs). FTSGs harvest sites generally require primary closure, which limits availability, especially when treating larger wounds. STSGs have many shortcomings, including donor site morbidity. Fractional autologous skin replacement can be utilized in conjunction with or in lieu of STSGs to both improve graft outcomes of large wounds and to decrease donor site morbidity. Skin can be mechanically or chemically fractionated. Fractionated skin can be advantageous, as adnexal structures provide additional functionality without donor site morbidity. In this review, we will discuss current and emerging techniques in fractional skin replacement.
对于无法进行一期缝合的伤口覆盖，金标准是全厚皮片（FTSG）和中厚皮片（STSG）。FTSG的供皮区通常需要一期缝合，这限制了其可用性，尤其是在治疗较大伤口时。STSG有许多缺点，包括供皮区并发症。自体皮肤部分替代可与STSG联合使用或替代STSG，以改善大伤口的植皮效果并降低供皮区并发症。皮肤可通过机械或化学方法进行分割。分割后的皮肤可能具有优势，因为附属结构可提供额外功能且无供皮区并发症。在本综述中，我们将讨论皮肤部分替代的当前和新兴技术。
