Suppr超能文献

与传统网状移植片相比,用于慢性伤口的切碎皮肤移植片。

Minced skin grafts for chronic wounds compared to conventional mesh grafts.

作者信息

Sanches-Pinto Débora C, Eriksson Elof, Gomez David S, Nunes Maria P T, Gemperli Rolf, Soriano Francisco G

机构信息

Divisão de Cirurgia Plástica e Queimaduras. Clinicas Hospital - School of Medicine University of São Paulo São Paulo Brazil.

Harvard Medical School Boston Massachusetts USA.

出版信息

Health Sci Rep. 2023 Jun 21;6(6):e1353. doi: 10.1002/hsr2.1353. eCollection 2023 Jun.

Abstract

BACKGROUND AND AIMS

Skin grafting is the single most effective method to close a chronic wound. The current standard of care is to use meshed split thickness skin grafts. This entails the use of surgical instruments that need to be autoclaved and to have a power source, which usually requires an OR facility. The minced skin technique uses single use, presterilized instruments and the procedure can be done under local anesthesia, by a wound care practitioner, in a wound clinic, a physician's office or even at the bedside. The current study was designed to determine if the results from micrografting were non inferior to conventional mesh grafting.

METHODS

In a prospective non inferiority study, 26 chronic ulcers were treated with micrografting (MSG) and 24 with conventional mesh grafts 1:3 (control group-CG) in a total of 21 patients, 10 male and 11 female. The donor site areas in the MSG group were predetermined to 2.5 × 5 cm and the mesh grafts expansion was set at 1:3.

RESULTS

In the first weeks postoperatively, micrograft healing initially lagged behind the conventional mesh grafts but at 60 days after grafting, all MSG wounds were healed. The MSG wounds had better pigmentation, less itching, and less scarring. The micrografting procedure was easy to learn and expeditious to perform. The MSG mean expansion was 9.1 compared to three times (CG).

CONCLUSION

The MSG procedure is not inferior to conventional mesh grafting, requires smaller donor sites, and can be done with single use instruments, under local anesthesia, with early discharge.

摘要

背景与目的

皮肤移植是闭合慢性伤口最有效的单一方法。当前的护理标准是使用网状中厚皮片。这需要使用需要高压灭菌且有电源的手术器械,而这通常需要手术室设施。碎皮技术使用一次性、预消毒的器械,该手术可在局部麻醉下由伤口护理从业者在伤口诊所、医生办公室甚至床边进行。本研究旨在确定微移植的结果是否不劣于传统网状移植。

方法

在一项前瞻性非劣效性研究中,21例患者(10例男性和11例女性)中的26处慢性溃疡采用微移植(MSG)治疗,24处采用传统网状移植1:3(对照组-CG)治疗。MSG组的供皮区面积预先设定为2.5×5cm,网状移植的扩张比例设定为1:3。

结果

术后最初几周,微移植愈合最初落后于传统网状移植,但在移植后60天,所有MSG伤口均愈合。MSG伤口色素沉着更好,瘙痒更少,瘢痕更少。微移植手术易于学习且操作迅速。MSG的平均扩张倍数为9.1,而对照组为三倍。

结论

MSG手术不劣于传统网状移植,需要的供皮区更小,可使用一次性器械在局部麻醉下进行,且患者可早期出院。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0201/10285033/a8d6664cddf2/HSR2-6-e1353-g003.jpg

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验