Culicetto Laura, Latella Desirèe, Lo Buono Viviana, Orecchio Fabio, Murdaca Anna Maria, Quartarone Angelo, Marino Silvia
IRCCS Centro Neurolesi "Bonino-Pulejo", S.S. 113 Via Palermo C. da Casazza, 98124 Messina, Italy.
Faculty of Human Sciences, Università Telematica Pegaso, 80143 Naples, Italy.
J Pers Med. 2025 Feb 27;15(3):92. doi: 10.3390/jpm15030092.
: In recent years, the popularity of non-verbal cognitive training for aphasia has increased. Building on evidence that language abilities engage brain areas involved in executive functions (EFs) processing, this review aims to analyze the utility of EFs training alone or combined with traditional rehabilitation approaches to improve language abilities in aphasia. : Systematic searches were performed in four databases evaluating studies focusing on the effects of EFs training in language rehabilitation, yielding 185 studies. After reading the full text of the selected studies and applying predefined inclusion criteria, nine studies were included based on pertinence and relevance to the topic. This systematic review has been registered in the Prospective Register of Systematic Reviews (PROSPERO 2024) with the number CRD42024519087. : The results of the analyzed studies indicate that various EFs training methods, such as computer-assisted executive control training, Cognitive Flexibility in Aphasia Therapy (CFAT), and the Dr. Neuronowski program, as well as the combination of transcranial direct current stimulation (tDCS) with EFs training, can lead to improvements in language abilities in people with aphasia. Additionally, EFs training often results in specific effects on treated functions like working memory (near transfer effects) and untreated ones such as spoken sentence comprehension (far transfer effects). : Despite the heterogeneity of the treatments and the small simple size of the studies analyzed, preliminary results are promising. Future research should further explore the effectiveness and specific contribution of EFs training to improving language functions in aphasia.
近年来，失语症的非言语认知训练越来越受欢迎。基于语言能力涉及执行功能（EFs）处理相关脑区的证据，本综述旨在分析单独进行EFs训练或与传统康复方法相结合对改善失语症患者语言能力的效用。：在四个数据库中进行了系统检索，评估聚焦于EFs训练对语言康复效果的研究，共获得185项研究。在阅读所选研究的全文并应用预定义的纳入标准后，基于与主题的相关性，纳入了9项研究。本系统综述已在系统评价前瞻性注册库（PROSPERO 2024）中注册，注册号为CRD42024519087。：分析研究的结果表明，各种EFs训练方法，如计算机辅助执行控制训练、失语症治疗中的认知灵活性训练（CFAT）和诺罗诺夫斯基博士项目，以及经颅直流电刺激（tDCS）与EFs训练的结合，都可以使失语症患者的语言能力得到改善。此外，EFs训练通常会对已治疗的功能（如工作记忆，近迁移效应）和未治疗的功能（如口语句子理解，远迁移效应）产生特定影响。：尽管所分析研究的治疗方法存在异质性且样本量较小，但初步结果很有前景。未来的研究应进一步探索EFs训练对改善失语症语言功能的有效性和具体贡献。
