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认知训练结合时间信息处理可改善失语症患者的语言和非语言功能。

Cognitive training incorporating temporal information processing improves linguistic and non-linguistic functions in people with aphasia.

机构信息

Laboratory of Neurophysiology of Mind, BRAINCITY-Center of Excellence for Neural Plasticity and Brain Disorders, Nencki Institute of Experimental Biology, Polish Academy of Sciences, Warsaw, Poland.

Faculty of Psychology, University of Warsaw, Warsaw, Poland.

出版信息

Sci Rep. 2023 Aug 28;13(1):14053. doi: 10.1038/s41598-023-41045-0.

Abstract

People with aphasia (PWA) often present deficits in non-linguistic cognitive functions, such as executive functions, working memory, and temporal information processing (TIP), which intensify the associated speech difficulties and hinder the rehabilitation process. Therefore, training targeting non-linguistic cognitive function deficiencies may be useful in the treatment of aphasia. The present study compared the effects of the novel Dr. Neuronowski training method (experimental training), which particularly emphasizes TIP, with the linguistic training commonly applied in clinical practice (control training). Thirty four PWA underwent linguistic and non-linguistic assessments before and after the training as well as a follow-up assessment. Patients were randomly assigned to either experimental (n = 18) or control groups (n = 16). The experimental training improved both non-linguistic functions (TIP and verbal short-term and working memory) and linguistic functions: phoneme discrimination, sentence comprehension, grammar comprehension, verbal fluency, and naming. In contrast, the control training improved only grammar comprehension and naming. The follow-up assessment confirmed the stability of the effects of both trainings over time. Thus, in PWA, Dr. Neuronowski training appears to have broader benefits for linguistic and non-linguistic functions than does linguistic training. This provides evidence that Dr. Neuronowski may be considered a novel tool with potential clinical applications.

摘要

失语症患者(PWA)常表现出非语言认知功能缺陷,如执行功能、工作记忆和时间信息处理(TIP),这加剧了相关的言语困难,并阻碍了康复过程。因此,针对非语言认知功能缺陷的训练可能对失语症的治疗有用。本研究比较了新型 Dr. Neuronowski 训练方法(实验组)与临床实践中常用的语言训练(对照组)对 TIP 的影响。34 名 PWA 在训练前后以及随访评估中进行了语言和非语言评估。患者被随机分配到实验组(n=18)或对照组(n=16)。实验组训练改善了非语言功能(TIP 以及言语短期和工作记忆)和语言功能:音素辨别、句子理解、语法理解、言语流畅性和命名。相比之下,对照组训练仅改善了语法理解和命名。随访评估证实了两种训练的效果在时间上的稳定性。因此,在 PWA 中,与语言训练相比,Dr. Neuronowski 训练似乎对语言和非语言功能有更广泛的益处。这提供了证据表明,Dr. Neuronowski 可能被视为一种具有潜在临床应用的新工具。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9550/10462731/f8fd26e12cf5/41598_2023_41045_Fig1_HTML.jpg

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