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心脏CT在心肌病表型分析中的应用

Utility of Cardiac CT for Cardiomyopathy Phenotyping.

作者信息

Ibrahim Ramzi, Abdelnabi Mahmoud, Pathangey Girish, Farina Juan, Lester Steven J, Ayoub Chadi, Alsidawi Said, Tamarappoo Balaji K, Jokerst Clinton, Arsanjani Reza

机构信息

Department of Cardiovascular Medicine, Mayo Clinic, Phoenix, AZ 85054, USA.

Department of Radiology, Mayo Clinic, Scottsdale, AZ 85054, USA.

出版信息

Tomography. 2025 Mar 20;11(3):39. doi: 10.3390/tomography11030039.

Abstract

Cardiac computed tomography (CT) has rapidly advanced, becoming an invaluable tool for diagnosing and prognosticating various cardiovascular diseases. While echocardiography and cardiac magnetic resonance imaging (CMR) remain the gold standards for myocardial assessment, modern CT technologies offer enhanced spatial resolution, making it an essential tool in clinical practice. Cardiac CT has expanded beyond coronary artery disease evaluation, now playing a key role in assessing cardiomyopathies and structural heart diseases. Innovations like photon-counting CT enable precise estimation of myocardial extracellular volume, facilitating the detection of infiltrative disorders and myocardial fibrosis. Additionally, CT-based myocardial strain analysis allows for the classification of impaired myocardial contractility, while quantifying cardiac volumes and function remains crucial in cardiomyopathy evaluation. This review explores the emerging role of cardiac CT in cardiomyopathy phenotyping, emphasizing recent technological advancements.

摘要

心脏计算机断层扫描(CT)发展迅速,已成为诊断和预测各种心血管疾病的重要工具。虽然超声心动图和心脏磁共振成像(CMR)仍是心肌评估的金标准,但现代CT技术提供了更高的空间分辨率,使其成为临床实践中的重要工具。心脏CT的应用范围已超越冠状动脉疾病评估,目前在心肌病和结构性心脏病的评估中发挥着关键作用。光子计数CT等创新技术能够精确估计心肌细胞外容积,有助于检测浸润性疾病和心肌纤维化。此外,基于CT的心肌应变分析可对心肌收缩功能受损进行分类,而在心肌病评估中,量化心脏容积和功能仍然至关重要。本综述探讨了心脏CT在心肌病表型分析中的新兴作用,重点介绍了近期的技术进展。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/68e0/11946596/15f8a4ff1c78/tomography-11-00039-g001.jpg

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