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经胆道镜引导下坏死组织清除术治疗胰源性后腹膜及直肠后坏死

Choledochoscope-Guided Necrosectomy for Retroperitoneal and Posterior Rectal Post-Pancreatitis Necrosis.

作者信息

Li Xin, Zhao Guang, Wang Cong-Yu, Zhang Gen, Feng Xiang-Lan, He Fei, Lei Shu-Lei, Cui Yun-Feng

机构信息

Tianjin Medical University, Tianjin, China.

Tianjin Nankai Hospital, Tianjin Medical University, Tianjin, China.

出版信息

Am J Case Rep. 2025 Mar 26;26:e946452. doi: 10.12659/AJCR.946452.

DOI:10.12659/AJCR.946452
PMID:40138261
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11957327/
Abstract

BACKGROUND Severe acute pancreatitis is a severe acute abdominal disease. Signs and symptoms classically vary from abdominal pain to fever, vomiting, and abdominal distension. Severe complications, such as infected pancreatic necrosis and multiple organ dysfunction syndrome, can occur. The various treatment strategies in acute necrotizing pancreatitis include percutaneous drainage, laparoscopic necrosectomy, endoscopic necrosectomy, and minimally invasive or more hazardous open surgery. In the presently described case, the effect of puncture drainage was not significant, and then choledochoscope-assisted pancreatic necrosectomy was performed. CASE REPORT In this case, a 41-year-old Chinese man developed extensive retroperitoneal necrosis extending into the posterior rectum following severe acute pancreatitis. The treatment of secondary infection of pancreatic necrotic tissue remains a major challenge. The drainage catheter for the abdominal puncture was inserted, but it was not effective enough. On the 45th day of admission, choledochoscope-assisted pancreatic necrosectomy was performed. After the operation, the patient was given continuous saline flushing through the drain and low continuous suction was applied to the lumen sump drain. We consider this to be a valuable case in which a patient improved in response to placement of a drain intraoperatively in the posterior rectum. CONCLUSIONS We report a patient who developed extensive retroperitoneal necrosis extending into the posterior rectum following severe acute pancreatitis. We decided to perform choledochoscope-assisted pancreatic necrosectomy; the necrotic tissue around the posterior rectum was removed and a triple lumen sump drain was placed in the posterior rectum. This is the first case of infection of the posterior rectal space after severe acute pancreatitis treated by choledochoscope-assisted pancreatic necrosectomy.

摘要

背景 重症急性胰腺炎是一种严重的急性腹部疾病。其体征和症状通常从腹痛到发热、呕吐及腹胀不等。可能会出现严重并发症,如感染性胰腺坏死和多器官功能障碍综合征。急性坏死性胰腺炎的各种治疗策略包括经皮引流、腹腔镜坏死组织清除术、内镜坏死组织清除术以及微创或更具风险的开放手术。在本病例中,穿刺引流效果不佳,随后进行了胆道镜辅助胰腺坏死组织清除术。

病例报告 本病例中,一名41岁中国男性在重症急性胰腺炎后发生广泛的腹膜后坏死并蔓延至直肠后方。胰腺坏死组织继发感染的治疗仍然是一项重大挑战。插入了腹部穿刺引流管,但效果不够理想。入院第45天,进行了胆道镜辅助胰腺坏死组织清除术。术后,通过引流管对患者进行持续生理盐水冲洗,并对腔隙引流管进行低负压持续吸引。我们认为这是一例通过术中在直肠后方放置引流管而使患者病情改善的有价值病例。

结论 我们报告了一名在重症急性胰腺炎后发生广泛腹膜后坏死并蔓延至直肠后方的患者。我们决定进行胆道镜辅助胰腺坏死组织清除术;切除了直肠后方的坏死组织,并在直肠后方放置了三腔腔隙引流管。这是首例采用胆道镜辅助胰腺坏死组织清除术治疗重症急性胰腺炎后直肠后间隙感染的病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d9c1/11957327/17c3976f84be/amjcaserep-26-e946452-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d9c1/11957327/b7a61ac97aa2/amjcaserep-26-e946452-g001.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d9c1/11957327/c2104442649b/amjcaserep-26-e946452-g003.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d9c1/11957327/8724c98436df/amjcaserep-26-e946452-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d9c1/11957327/e0bb721071cb/amjcaserep-26-e946452-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d9c1/11957327/c010d7dd8e7a/amjcaserep-26-e946452-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d9c1/11957327/17c3976f84be/amjcaserep-26-e946452-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d9c1/11957327/b7a61ac97aa2/amjcaserep-26-e946452-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d9c1/11957327/8ed635c9a889/amjcaserep-26-e946452-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d9c1/11957327/c2104442649b/amjcaserep-26-e946452-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d9c1/11957327/6cea7d139fee/amjcaserep-26-e946452-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d9c1/11957327/a12502dab41d/amjcaserep-26-e946452-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d9c1/11957327/8724c98436df/amjcaserep-26-e946452-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d9c1/11957327/e0bb721071cb/amjcaserep-26-e946452-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d9c1/11957327/c010d7dd8e7a/amjcaserep-26-e946452-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d9c1/11957327/17c3976f84be/amjcaserep-26-e946452-g009.jpg

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DEN Open. 2022 Apr 23;2(1):e120. doi: 10.1002/deo2.120. eCollection 2022 Apr.
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