Inmon J, Vaughan T, Morris J
Am Ind Hyg Assoc J. 1985 Jun;46(6):303-7. doi: 10.1080/15298668591394860.
A limited-access facility has been designed as a result of the need for laboratories for testing hazardous materials found in the environment. The facility design features include room air flow and filtration, hood types, sink design and placement, design of countertops, type of flooring and wall sealant, and traffic flow within the laboratories. These laboratories required the diversity to handle weighing of stock hazardous materials, preparation and handling of aliquots, maintenance of dosed animals as well as sterile conditions required for tissue culture and continuous cell culture methods. A safety and health program was also developed which included specific dress (e.g., scrub suit, TYVEK jumpsuit, gloves, safety glasses and safety shoes), safety advisory group, safety response group, medical monitoring program and training of current and new staff members. The design and use of the facility are continuously reevaluated and changes are made as necessitated by either research needs or improved safety methods.
由于需要用于检测环境中发现的有害物质的实验室，因此设计了一个有限进入设施。该设施的设计特点包括室内气流和过滤、通风柜类型、水槽设计和放置、台面设计、地板和墙壁密封剂类型以及实验室内的人流。这些实验室需要具备多种功能，以处理库存有害物质的称重、等分试样的制备和处理、实验动物的饲养以及组织培养和连续细胞培养方法所需的无菌条件。还制定了一项安全与健康计划，其中包括特定着装（如手术服、特卫强连体工作服、手套、安全眼镜和安全鞋）、安全咨询小组、安全应急小组、医疗监测计划以及对现有和新员工的培训。该设施的设计和使用不断重新评估，并根据研究需求或改进的安全方法进行必要的更改。
