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磁场疗法(AT - 04)对血液透析中动静脉内瘘穿刺时疼痛减轻的影响。

Effects of magnetic field therapy (AT-04) on pain reduction during arteriovenous fistula puncture in hemodialysis.

作者信息

Tsuchiya Yukiko, Uchiyama Taketo, Kato Kazuhiko, Nakashima Akio, Tokudome Goro, Yokoo Takashi

机构信息

Division of Nephrology and Hypertension, The Jikei University School of Medicine, Tokyo, Japan.

Division of Nephrology, Tokyu Hospital, Tokyo, Japan.

出版信息

Clin Exp Nephrol. 2025 Mar 26. doi: 10.1007/s10157-025-02666-z.

Abstract

BACKGROUND

Pain from arteriovenous fistula puncture significantly affects the quality of life of patients undergoing hemodialysis. AT-04 was designed to alleviate this pain using magnetic stimulation, which is anticipated to be beneficial for managing pain across different conditions. However, limited research exists on the effectiveness of AT-04 in diminishing the pain related to arteriovenous fistula puncture in hemodialysis patients.

METHODS

Between July and August 2024, we enrolled 14 outpatient maintenance hemodialysis patients at Tokyu Hospital who had given informed consent. AT-04 was administered before arteriovenous fistula puncture. We assessed the pain intensity of the puncture using the Visual Analog Scale (VAS) before the application of AT-04, as well as at one and four weeks afterward. We observed changes in puncture pain levels before and after the AT-04 application.

RESULTS

The participants had an average age of 80 years (IQR, 74-85) and a mean dialysis duration of 5.8 years (IQR, 1.0-8.9). Lidocaine tape was utilized by 71.4% of participants, painkillers by 7.1%, and 28.6% used sleeping pills, with none taking antidepressants. The median VAS score before starting AT-04 was 40.5 (IQR, 23.5-55.5). One week after starting AT-04, the median VAS score dropped to 27.0 (IQR, 4.5-32.8), and four weeks later, it further decreased to 16.5 (IQR, 5.0-38.8). These decreases were statistically significant compared to the pre-treatment VAS score (one week after p = 0.0057, four weeks after p = 0.0076).

CONCLUSION

The AT-04 device, which uses alternating magnetic field therapy, significantly alleviated pain from arteriovenous fistula puncture in hemodialysis patients.

摘要

背景

动静脉内瘘穿刺疼痛显著影响血液透析患者的生活质量。AT - 04旨在通过磁刺激缓解这种疼痛,预计对不同情况下的疼痛管理有益。然而,关于AT - 04减轻血液透析患者动静脉内瘘穿刺相关疼痛有效性的研究有限。

方法

2024年7月至8月期间,我们招募了东京急行医院14名签署知情同意书的门诊维持性血液透析患者。在动静脉内瘘穿刺前使用AT - 04。我们在应用AT - 04前、应用后1周和4周使用视觉模拟评分法(VAS)评估穿刺的疼痛强度。我们观察了AT - 04应用前后穿刺疼痛水平的变化。

结果

参与者的平均年龄为80岁(四分位间距,74 - 85岁),平均透析时长为5.8年(四分位间距,1.0 - 8.9年)。71.4%的参与者使用利多卡因贴剂,7.1%使用止痛药,28.6%使用安眠药,无人服用抗抑郁药。开始使用AT - 04前的VAS评分中位数为40.5(四分位间距,23.5 - 55.5)。开始使用AT - 04 1周后,VAS评分中位数降至27.0(四分位间距,4.5 - 32.8),4周后进一步降至16.5(四分位间距,5.0 - 38.8)。与治疗前VAS评分相比,这些下降具有统计学意义(1周后p = 0.0057,4周后p = 0.0076)。

结论

使用交变磁场疗法的AT - 04设备显著减轻了血液透析患者动静脉内瘘穿刺的疼痛。

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