Chemotherapy-induced peripheral neuropathy (CIPN) is a common and often persistent adverse effect of several anticancer agents, leading to impaired physical function and quality of life. Although exercise therapy and physical modalities such as transcutaneous electrical nerve stimulation have been reported to alleviate CIPN symptoms, the efficacy of alternating magnetic field therapy remains unclear. We here report a rectal cancer survivor who experienced difficulty returning to work due to persistent neuropathic symptoms of CIPN. A combination of exercise therapy and alternating magnetic field therapy improved the patient's physical function and pain, ultimately enabling his return to work. This case highlights the potential utility of combining rehabilitation and alternating magnetic field therapy in CIPN management.