McGrady G A, Daling J R, Peterson D R
Am J Epidemiol. 1985 Mar;121(3):377-81. doi: 10.1093/oxfordjournals.aje.a114009.
The relationship of acute urinary tract infection occurring during pregnancy and the incidence of adverse fetal outcomes was examined with the use of birth certificate data from Washington state for the years 1980 and 1981. The two-year fetal mortality rate among urinary tract infection-associated pregnancies was found to be 17.9 per thousand livebirths, 2.4 times the rate for the state as a whole. Low birth weight newborns and small for gestational age newborns were, respectively, 2.04 and 1.57 times more frequent in urinary tract infection-associated pregnancies compared to controls. These estimates of risk were unchanged when adjusted for maternal age, race, and past obstetric history. The risk of prematurity in women with urinary tract infection and no history of fetal loss was 2.4 times the control risk. Sepsis was rare in both the urinary tract infection and control groups. These results add to the evidence implicating maternal urinary tract infection as a threat to fetal well-being.
利用华盛顿州1980年和1981年的出生证明数据，研究了孕期发生的急性尿路感染与不良胎儿结局发生率之间的关系。在与尿路感染相关的妊娠中，两年的胎儿死亡率为每千例活产17.9例，是该州总体死亡率的2.4倍。与对照组相比，与尿路感染相关的妊娠中低体重新生儿和小于胎龄新生儿的发生率分别高出2.04倍和1.57倍。在对产妇年龄、种族和既往产科病史进行调整后，这些风险估计值没有变化。有尿路感染且无胎儿丢失史的妇女早产风险是对照组的2.4倍。败血症在尿路感染组和对照组中均很少见。这些结果进一步证明了产妇尿路感染对胎儿健康构成威胁。
