Wnuk-Scardaccione Agnieszka, Bilski Jan
Department of Biomechanics and Kinesiology, Institute of Physiotherapy, Chair of Biomedical Sciences, Faculty of Health Sciences, Jagiellonian University Medical College, 8 Skawińska Street, 31-066 Krakow, Poland.
Medicina (Kaunas). 2025 Mar 20;61(3):542. doi: 10.3390/medicina61030542.
Limb amputation remains a significant global health issue, affecting millions of individuals annually. A substantial proportion of these patients struggle with the inadequate fit and discomfort of conventional prosthetic sockets, leading to diminished quality of life. Osseointegration surgery, a promising alternative, offers the direct skeletal attachment of bone, implant, and prosthetic, providing a more stable and functional interface. Osseointegration remains an emerging procedure, and while exact global figures are difficult to pinpoint, estimates suggest that over 10,000 patients worldwide have received osseointegration implants since the technique was first introduced. This perspective article analyzes recent advancements in the field of limb osseointegration, highlighting key achievements such as improved implant materials, surgical techniques, and comprehensive prosthetic integration strategies. Additionally, it explores future directions for development and discusses the latest research trends shaping the evolution of this field. Despite these developments, the widespread adoption of osseointegration faces significant barriers, including complications, limited access to multidisciplinary care, economic constraints, and the need for further long-term clinical evidence. In this paper, we present an extensive perspective on the current state of osseointegration, discuss the challenges impeding its broader implementation, and offer recommendations to address these obstacles, with the goal of enhancing patient outcomes and facilitating the integration of osseointegration into mainstream clinical practice.
肢体截肢仍然是一个重大的全球健康问题，每年影响着数百万人。这些患者中有很大一部分人面临传统假肢接受腔贴合不佳和不适的问题，导致生活质量下降。骨整合手术是一种很有前景的替代方法，它能实现骨骼、植入物和假肢的直接骨骼连接，提供更稳定且功能更强的界面。骨整合仍然是一种新兴手术，虽然难以确定确切的全球数据，但据估计，自该技术首次引入以来，全球已有超过10000名患者接受了骨整合植入物。这篇观点文章分析了肢体骨整合领域的最新进展，突出了诸如改进植入材料、手术技术和全面的假肢整合策略等关键成就。此外，还探讨了未来的发展方向，并讨论了塑造该领域发展的最新研究趋势。尽管有这些进展，但骨整合的广泛应用仍面临重大障碍，包括并发症、多学科护理的可及性有限、经济限制以及需要更多长期临床证据。在本文中，我们对骨整合的现状进行了广泛的阐述，讨论了阻碍其更广泛应用的挑战，并提出了解决这些障碍的建议，目标是改善患者预后并促进骨整合融入主流临床实践。
