Petakh Pavlo, Kamyshnyi Oleksandr
Department of Biochemistry and Pharmacology, Uzhhorod National University, 88000 Uzhhorod, Ukraine.
Department of Microbiology, Virology, and Immunology, I. Horbachevsky Ternopil National Medical University, 46001 Ternopil, Ukraine.
Microorganisms. 2025 Mar 7;13(3):614. doi: 10.3390/microorganisms13030614.
Leptospirosis is a zoonotic disease caused by bacteria, which affects both humans and animals. This study investigated the prevalence of serogroups in human and rodent reservoirs across Zakarpattia Oblast, Ukraine, from 2018 to 2023. The objective was to identify epidemiological patterns and assess potential public health risks. Data were sourced from the Public Health Center of Ukraine and regional surveillance initiatives, encompassing reported human cases and rodent-carrier detection. Six main serogroups-Icterohaemorrhagiae, Pomona, Grippotyphosa, Hebdomadis, Canicola, and Tarassovi-were included in the analysis. The results showed that Pomona and Hebdomadis serogroups became more common in 2023. The data from different districts also showed regional differences, with Icterohaemorrhagiae and Pomona being the most frequent serogroups in both humans and rodents. Other serogroups, like Grippotyphosa and Canicola, were found less often. Rodents may be an important source of leptospirosis in Zakarpattia. The growing number of cases in recent years shows the need for improved monitoring, control, and prevention in the region.
钩端螺旋体病是一种由细菌引起的人畜共患病，会影响人类和动物。本研究调查了2018年至2023年乌克兰外喀尔巴阡州人类和啮齿动物宿主中血清群的流行情况。目的是确定流行病学模式并评估潜在的公共卫生风险。数据来自乌克兰公共卫生中心和区域监测倡议，包括报告的人类病例和啮齿动物携带者检测。分析包括六个主要血清群——出血性黄疸型、波摩那型、犬伤寒型、七日热型、犬型和塔拉索夫型。结果显示，波摩那型和七日热型血清群在2023年变得更为常见。不同地区的数据也显示出区域差异，出血性黄疸型和波摩那型是人类和啮齿动物中最常见的血清群。其他血清群，如犬伤寒型和犬型，则较少发现。啮齿动物可能是外喀尔巴阡州钩端螺旋体病的重要来源。近年来病例数量的增加表明该地区需要加强监测、控制和预防。
