Lupi Ettore, Ciccozzi Alessandra, Becelli Roberto, Mannino Mario, Bernardi Sara, Giovannetti Filippo
Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, 67100 L'Aquila, Italy.
Department of Life, Health and Environmental Sciences, University of L'Aquila, 67100 L'Aquila, Italy.
J Clin Med. 2025 Mar 17;14(6):2033. doi: 10.3390/jcm14062033.
Cocaine is a recreational drug known for its negative impact on health and social and economic life. One of the complications for cocaine abusers is cocaine-induced midline destructive lesion (CIMDL) syndrome, which includes the extensive destruction of the osteocartilaginous structures of the nose, the sinus, and the palate. Here, we describe three cases of the surgical management of CIMDL using a temporalis muscle flap combined with a Le Fort I osteotomy, which allows sufficient space for the muscle to settle. The addition of the osteotomy allowed better handling of the pedicled flap, with no signs of relapse in the reported cases and high patient satisfaction. CIMDL syndrome is an impairing disease that negatively affects the functionality of the nasal and oral cavities, as well as the aesthetic. Surgical repair using a pedicled flap is a valid option in rehabilitated and sober patients with endothelial damage.
可卡因是一种消遣性毒品,因其对健康以及社会和经济生活产生负面影响而闻名。可卡因滥用者的并发症之一是可卡因诱发的中线破坏性病变(CIMDL)综合征,其中包括鼻子、鼻窦和腭部的骨软骨结构广泛破坏。在此,我们描述了3例采用颞肌瓣联合Le Fort I截骨术治疗CIMDL的手术案例,该手术能为肌肉植入提供足够空间。截骨术的加入使带蒂皮瓣的处理更加容易,在报告的案例中未出现复发迹象,患者满意度较高。CIMDL综合征是一种致残性疾病,会对鼻腔和口腔功能以及美观产生负面影响。对于有内皮损伤的康复且清醒的患者,使用带蒂皮瓣进行手术修复是一种有效的选择。