Pawłowski Wojciech, Urban Beata, Zawistowska Joanna, Bakunowicz-Łazarczyk Alina
Department of Paediatric Ophthalmology and Strabismus, Medical University of Bialystok, ul. Waszyngtona 17, 15-274 Bialystok, Poland.
J Clin Med. 2025 Mar 19;14(6):2104. doi: 10.3390/jcm14062104.
: The aim of our study is to evaluate the efficacy of pranoprofen 0.1% in preventing the occurrence of postoperative complications, including postoperative ocular inflammation after strabismus surgery in children. 90 children operated on for strabismus in the Department of Paediatric Ophthalmology and Strabismus of the Medical University of Bialystok between 2022 and 2023 were included in the study. The patients were aged from 2 to 17 years old. Patients were divided into three groups of 30 patients according to the method of topical postoperative treatment (group I: tobramycin, pranoprofen, dexpanthenol; group II: tobramycin, dexamethasone, dexpanthenol; group III: tobramycin, pranoprofen, dexamethasone, dexpanthenol). Patients were followed up the day after surgery, on postoperative day 14 and then 3 months after surgery. : No child showed signs of postoperative infection. There was one case of allergic reaction each in groups I and III. Most complications were present in group II (six cases: there were allergic reactions that occurred in three patients. Two patients experienced a complication in the form of delle, while one patient developed a granuloma), which was a statistically significant difference compared to groups I and III ( = 0.032). : Pranoprofen used postoperatively is as effective as a glucocorticosteroid, and from our observations, carries fewer complications in cases requiring prolonged use of the anti-inflammatory treatment. Systematic postoperative follow-up is essential for the diagnosis and possible management of postsurgical complications.
我们研究的目的是评估0.1%的普拉洛芬在预防术后并发症发生方面的疗效,这些并发症包括儿童斜视手术后的眼部炎症。2022年至2023年期间,在比亚韦斯托克医科大学小儿眼科与斜视科接受斜视手术的90名儿童被纳入该研究。患者年龄在2至17岁之间。根据术后局部治疗方法,患者被分为三组,每组30人(第一组:妥布霉素、普拉洛芬、泛醇;第二组:妥布霉素、地塞米松、泛醇;第三组:妥布霉素、普拉洛芬、地塞米松、泛醇)。术后第一天、术后第14天以及术后3个月对患者进行随访。:没有儿童出现术后感染迹象。第一组和第三组各有1例过敏反应。大多数并发症出现在第二组(6例:3名患者出现过敏反应。2名患者出现了角膜上皮剥脱形式的并发症,1名患者出现了肉芽肿),与第一组和第三组相比,这具有统计学显著差异(P = 0.032)。:术后使用的普拉洛芬与糖皮质激素一样有效,并且根据我们的观察,在需要长期使用抗炎治疗的情况下,其并发症较少。术后系统随访对于诊断和处理术后并发症至关重要。