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经皮撤除HeartWare左心室辅助装置(HVAD)支持后的长期结局:10年随访更新

Long-term outcomes after percutaneous withdrawal of HeartWare left ventricular assist device (HVAD) support: A 10-year update.

作者信息

Thaitirarot Chokanan, Shapiro Leonard M, Lewis Clive, Parameshwar Jayan, Tsui Steven S L, Pettit Stephen J

机构信息

Transplant Unit, Royal Papworth Hospital, Royal Papworth Hospital NHS Foundation Trust, Cambridge, UK.

Cardiology Centre, Chulabhorn Hospital, Chulabhorn Royal Academy, Bangkok, Thailand.

出版信息

JHLT Open. 2024 Oct 23;7:100169. doi: 10.1016/j.jhlto.2024.100169. eCollection 2025 Feb.

DOI:10.1016/j.jhlto.2024.100169
PMID:40144815
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11935337/
Abstract

Ten years have passed since we reported percutaneous decommissioning of an implantable left ventricular assist device (LVAD) using 2 Amplatzer vascular plugs in a 17-year-old male who was bridged to recovery after 22 months of LVAD support. While his left ventricular (LV) dimensions never completely normalized and there has been persistent mild impairment of LV systolic function, the patient remains free of heart failure symptoms and his natriuretic peptide level has been well suppressed on guideline-directed medical therapy. He is anticoagulated with Warfarin. There have been no adverse events relating to either the decommissioned LVAD or the percutaneous driveline remnant, or anticoagulation. This case highlights the potential for long-term survival without adverse events in individuals who are left with a redundant implantable LVAD after successful percutaneous withdrawal of mechanical circulatory support.

摘要

自从我们报道了在一名17岁男性患者中使用2个Amplatzer血管封堵器经皮停用植入式左心室辅助装置(LVAD)以来,已经过去了十年。该患者在接受LVAD支持22个月后过渡到康复状态。虽然他的左心室(LV)尺寸从未完全恢复正常,并且LV收缩功能一直存在轻度损害,但该患者仍无心力衰竭症状,并且在指南指导的药物治疗下,他的利钠肽水平得到了很好的抑制。他使用华法林进行抗凝治疗。与停用的LVAD、经皮驱动线残余物或抗凝治疗均未发生不良事件。该病例突出了在成功经皮撤除机械循环支持后,体内留有多余植入式LVAD的个体实现长期生存且无不良事件的可能性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/56aa/11935337/eeea2e5830c6/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/56aa/11935337/ecb6de793b63/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/56aa/11935337/cd136444a1ac/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/56aa/11935337/eeea2e5830c6/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/56aa/11935337/ecb6de793b63/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/56aa/11935337/cd136444a1ac/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/56aa/11935337/eeea2e5830c6/gr3.jpg

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本文引用的文献

1
Percutaneous approach to left ventricular assist device decommissioning.经皮左心室辅助装置拆除术。
Catheter Cardiovasc Interv. 2022 Jul;100(1):169-174. doi: 10.1002/ccd.30230. Epub 2022 May 17.
2
Evaluation for Heart Transplantation and LVAD Implantation: JACC Council Perspectives.心脏移植与左心室辅助装置植入的评估:美国心脏病学会理事会观点。
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Left Ventricular Assist Device Decommissioning Compared with Explantation for Ventricular Recovery: A Systematic Review.
左心室辅助装置撤机与心室恢复的再植入:系统评价。
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Ventricular Recovery and Pump Explantation in Patients Supported by Left Ventricular Assist Devices: A Systematic Review.左心室辅助装置支持下患者的心室恢复与泵取出:一项系统评价
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Surgical approach to continuous-flow left ventricular assist device explantation: A comparison of outcomes.连续流左心室辅助装置取出术的手术方法:结果比较
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Percutaneous withdrawal of HeartWare HVAD left ventricular assist device support.经皮撤除HeartWare HVAD左心室辅助装置支持。
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J Heart Lung Transplant. 2014 Jun;33(6):555-64. doi: 10.1016/j.healun.2014.04.010. Epub 2014 Apr 21.
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Heartmate II outflow graft ligation and driveline excision without pump removal for left ventricular recovery.不拆除泵,进行Heartmate II流出道移植物结扎和驱动线切除以促进左心室恢复。
Proc (Bayl Univ Med Cent). 2012 Oct;25(4):344-5. doi: 10.1080/08998280.2012.11928872.
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Left ventricular assist device and drug therapy for the reversal of heart failure.左心室辅助装置与药物治疗用于心力衰竭的逆转
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