Zhang Xin, Wu Haixiu, Guo Shenchao, Zhu Tiepei, Xiang Zhenyang, Li Gaochun, Li Enhui
Department of Ophthalmology, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Taizhou, China.
Eye Center, Second Affiliated Hospital of Medical College, Zhejiang University, Hangzhou, China.
Front Med (Lausanne). 2025 Mar 12;12:1549152. doi: 10.3389/fmed.2025.1549152. eCollection 2025.
This study aimed to evaluate the efficacy of a modified pneumatic retinopexy (PR) procedure for patients with rhegmatogenous retinal detachment (RRD), particularly those with multiple-quadrant retinal breaks that spanning more than three clock-hours of retinal arc.
This prospective case series included ten eyes of ten patients, all of whom underwent the PR surgery during hospitalization. The modified PR technique involved an intravitreal injection of a low concentration of perfluoropropane (14% CF) for gas tamponade and head positioning maneuvers guided by an indicator. The multiple breaks were closed by gas bubble and treated with immediate laser photocoagulation one by one during the sequential alternating head positioning maneuver.
After the modified PR surgery, retinal attachment was achieved in 9 of the 10 eyes (90%). The single case of failure, due to significant vitreous hemorrhage following gas injection, underwent a vitrectomy and received retinal attachment. Permanent retinal attachment was achieved in all cases (100%) at the last follow-up with no adverse events. The mean preoperative best-corrected visual acuity was improved significantly at 6 months post-surgery.
This study demonstrates the potential of modified PR to achieve high success rates in RRD cases with multiple-quadrant retinal breaks cases involving superior retinal detachments and early proliferative vitreoretinopathy.
本研究旨在评估改良式气体视网膜固定术(PR)治疗孔源性视网膜脱离(RRD)患者的疗效,尤其是那些视网膜裂孔跨越超过三个钟点视网膜弧度的多象限视网膜裂孔患者。
本前瞻性病例系列纳入了10例患者的10只眼,所有患者均在住院期间接受了PR手术。改良的PR技术包括玻璃体腔内注射低浓度全氟丙烷(14%CF)进行气体填塞,并在指示器引导下进行头部定位操作。在连续交替头部定位操作过程中,通过气泡封闭多个裂孔,并逐一立即进行激光光凝治疗。
改良PR手术后,10只眼中有9只(90%)实现了视网膜复位。唯一一例失败病例是由于气体注射后出现大量玻璃体积血,随后接受了玻璃体切除术并实现了视网膜复位。在最后一次随访时,所有病例(100%)均实现了永久性视网膜复位,且无不良事件发生。术后6个月时,术前平均最佳矫正视力有显著改善。
本研究表明,改良式PR在治疗伴有视网膜上脱离和早期增生性玻璃体视网膜病变的多象限视网膜裂孔性RRD病例中具有取得高成功率的潜力。