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高强度聚焦超声无创治疗子宫肌瘤和子宫腺肌病疗效及安全性的回顾性队列研究

Retrospective cohort study on the efficacy and safety of high-intensity focused ultrasound in non-invasive treatment of uterine leiomyomas and adenomyosis.

作者信息

Su Zhan, Liu Sha, Wang Jiulan, Jin Fengying, Peng Youjin, Wen Junjie

机构信息

Guang'an People's Hospital, Guangan, China.

出版信息

Abdom Radiol (NY). 2025 Mar 27. doi: 10.1007/s00261-025-04908-w.

DOI:10.1007/s00261-025-04908-w
PMID:40146310
Abstract

OBJECTIVE

To assess the advantages of High-Intensity Focused Ultrasound (HIFU) in the treatment of uterine leiomyomas and adenomyosis.

METHODS

Patients with uterine leiomyomas (435 cases) and adenomyosis (78 cases) treated in our hospital from March 2020 to October 2023 were selected to receive non-invasive treatment with HIFU. Clinical symptom improvement and fibroid shrinkage were observed, and the incidence of complications and adverse reactions during and after treatment were analyzed.

RESULTS

The success rate of HIFU treatment in 435 cases of uterine leiomyomas was as high as 94.71%. The success rate of HIFU treatment was 96.15% in 78 cases of adenomyosis. Compared with before treatment, the improvement of clinical symptoms and the reduction of leiomyomas at one month, three months and six months after treatment were relatively better than those at the treatment period (P < 0.05). There were no serious adverse reactions in the patients during the treatment.

CONCLUSION

The noninvasive application of HIFU on leiomyomas and adenomyosis effectively improves the clinical symptoms of patients, and the volume of fibroids decreases significantly. At the same time, HIFU is safe and worthy of clinical application.

摘要

目的

评估高强度聚焦超声(HIFU)治疗子宫肌瘤和子宫腺肌病的优势。

方法

选取2020年3月至2023年10月在我院接受治疗的子宫肌瘤患者(435例)和子宫腺肌病患者(78例),采用HIFU进行无创治疗。观察临床症状改善情况及肌瘤缩小情况,并分析治疗期间及治疗后的并发症和不良反应发生率。

结果

435例子宫肌瘤患者的HIFU治疗成功率高达94.71%。78例子宫腺肌病患者的HIFU治疗成功率为96.15%。与治疗前相比,治疗后1个月、3个月和6个月时临床症状的改善及肌瘤缩小情况均优于治疗期间(P < 0.05)。治疗期间患者未出现严重不良反应。

结论

HIFU无创应用于子宫肌瘤和子宫腺肌病可有效改善患者临床症状,肌瘤体积显著减小。同时,HIFU安全,值得临床应用。

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Effects of different treatment methods on clinical efficacy and fertility outcomes of patients with adenomyosis.不同治疗方法对子宫腺肌病患者临床疗效及生育结局的影响。
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Reproductive and Obstetric Outcomes after UAE, HIFU, and TFA of Uterine Fibroids: Systematic Review and Meta-Analysis.UAE、HIFU 和 TFA 治疗子宫肌瘤的生殖和产科结局:系统评价和荟萃分析。
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Evaluation of high intensity focused ultrasound treatment for different types of adenomyosis based on magnetic resonance imaging classification.
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Comprehensive Review of Uterine Fibroids: Developmental Origin, Pathogenesis, and Treatment.子宫肌瘤的综合综述:发育起源、发病机制和治疗。
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Comparative Effectiveness and Safety of High-Intensity Focused Ultrasound for Uterine Fibroids: A Systematic Review and Meta-Analysis.高强度聚焦超声治疗子宫肌瘤的比较有效性和安全性:一项系统评价与荟萃分析
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Clinical effectiveness and potential long-term benefits of high-intensity focused ultrasound therapy for patients with adenomyosis.高强度聚焦超声治疗子宫腺肌病的临床疗效及潜在长期获益。
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Origin and Pathogenic Mechanisms of Uterine Adenomyosis: What Is Known So Far.子宫腺肌病的起源和发病机制:目前已知情况
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A comparison of reproductive outcomes of patients with adenomyosis and infertility treated with High-Intensity focused ultrasound and laparoscopic excision.高强度聚焦超声与腹腔镜切除治疗子宫腺肌病合并不孕患者的妊娠结局比较。
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