异维甲酸在隆鼻手术患者中的应用。
Isotretinoin use in rhinoplasty patients.
作者信息
Santana Jholbert Cardoso, Lisboa Hugo Valter Ramos, Camargo Leandro Azevedo de, Almeida Ricardo Araújo Meira, Bueno Lourival Mendes
机构信息
Hospital das Clínicas da Universidade Federal de Goiás (HC-UFG), Departamento de Otorrinolaringologia e Cirurgia de Cabeça e Pescoço, Goiânia, GO, Brazil.
Hospital das Clínicas da Universidade Federal de Goiás (HC-UFG), Departamento de Otorrinolaringologia e Cirurgia de Cabeça e Pescoço, Goiânia, GO, Brazil.
出版信息
Braz J Otorhinolaryngol. 2025 Jul-Aug;91(4):101592. doi: 10.1016/j.bjorl.2025.101592. Epub 2025 Mar 26.
OBJECTIVE
Presenting evidence available on perioperative isotretinoin application in, and benefits for, thick-skinned patients subjected to rhinoplasty.
METHODS
Analysis was applied to articles available in the following databases: Cochrane, PubMed, ScienceDirect and Scielo. The analyzed corpus comprised studies published from 2004 to 2023 focused on investigating thick-skinned patients subjected to rhinoplasty and treated with isotretinoin. Inappropriate and unrelated methodologies were excluded from the analysis.
RESULTS
Initially, 1,214 articles were collected, but this number dropped to 617 after duplicates' removal. Twenty (20) articles remained in the corpus after inclusion criteria application, but 10 of them were excluded from the analysis based on exclusion criteria. Finally, 10 articles were selected for review purposes: 1 experience report, 2 case studies, 3 narrative reviews and 4 clinical trials.
CONCLUSIONS
The current findings suggested aesthetic improvements in patients treated with isotretinoin, although its long-term benefits remain uncertain. Thus, further research on this topic should be conducted.
目的
提供关于厚皮患者在鼻整形术中应用围手术期异维甲酸及其益处的现有证据。
方法
对以下数据库中的文章进行分析：Cochrane、PubMed、ScienceDirect和Scielo。分析的语料库包括2004年至2023年发表的研究，重点是调查接受鼻整形术并接受异维甲酸治疗的厚皮患者。分析中排除了不适当和不相关的方法。
结果
最初收集了1214篇文章，但去除重复项后，这一数字降至617篇。应用纳入标准后，语料库中保留了20篇文章，但根据排除标准，其中10篇被排除在分析之外。最后，选择了10篇文章进行综述：1篇经验报告、2篇案例研究、3篇叙述性综述和4篇临床试验。
结论
目前的研究结果表明，接受异维甲酸治疗的患者在美学方面有所改善，但其长期益处仍不确定。因此，应就此主题进行进一步研究。
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