Ferreira Thales Victor Fernandes, Fernandes Ana Luíza Cézar, Espósito Mário Pinheiro
Hospital Otorrino, Cuiabá, MT, Brazil.
Centro Universitário de São Pessoa (UNIPE), João Pessoa, PB, Brazil.
Braz J Otorhinolaryngol. 2025 Jan-Feb;91(1):101498. doi: 10.1016/j.bjorl.2024.101498. Epub 2024 Sep 2.
To comprehensively analyze the benefits and harms associated with the use of isotretinoin as a skin preparation agent for rhinoplasty.
A systematic review of the literature was carried out, conducted through a comprehensive search in scientific databases: LILACS and PUBMED.
Although isotretinoin has beneficial effects on skin preparation, some studies indicate that its continuous use before rhinoplasty may interfere with healing, suggesting the need for a period of suspension prior to the procedure. Other concerns include the impact on blood levels, increasing the risk of hematological changes, highlighting the importance of regular hematological monitoring during treatment. The decision to use isotretinoin as preparation for rhinoplasty must take into account the surgeon's experience and the specific characteristics of the patient, seeking to balance the aesthetic benefits with the potential risks.
The decision to use isotretinoin as part of skin preparation for rhinoplasty must be individualized, taking into account the specific characteristics of the patient, their aesthetic objectives and the assessment of risks and benefits. A collaborative approach between the plastic surgeon, dermatologist and patient is essential to ensure safe and effective use of isotretinoin, maximizing its benefits while minimizing the potential harm associated with this therapy.
全面分析异维甲酸作为鼻整形术皮肤准备剂使用时的益处和危害。
通过在科学数据库LILACS和PUBMED中进行全面检索，对文献进行系统综述。
尽管异维甲酸对皮肤准备有有益作用，但一些研究表明，在鼻整形术前持续使用可能会干扰愈合，这表明在手术前需要有一段停药期。其他问题包括对血液水平的影响，增加血液学变化的风险，突出了治疗期间定期进行血液学监测的重要性。决定将异维甲酸用作鼻整形术的准备剂时，必须考虑外科医生的经验和患者的具体特征，力求在美学益处与潜在风险之间取得平衡。
决定将异维甲酸用作鼻整形术皮肤准备的一部分时，必须因人而异，考虑患者的具体特征、美学目标以及风险和益处评估。整形外科医生、皮肤科医生和患者之间的协作方法对于确保安全有效地使用异维甲酸至关重要，要在最大限度地发挥其益处的同时，将与该疗法相关的潜在危害降至最低。
