Nanda Atul K, Walcott Anthony, Goodnough Monica, Bernardez-Lai Sara, Villamil Sebastian
Humboldt Park Health, Chicago, IL 60622, USA; St. George's University School of Medicine, Grenada.
St. George's University School of Medicine, Grenada.
Int J Surg Case Rep. 2025 Apr;129:111179. doi: 10.1016/j.ijscr.2025.111179. Epub 2025 Mar 19.
Gastric cancers are silent malignancies that are typically diagnosed at advanced stages. Similarly, patients with prostate cancer can have an asymptomatic presentation despite widespread metastasis. The insidious nature of both malignancies highlights the importance of implementing appropriate screening protocols for early detection, prompt treatment, and better patient outcomes.
A 66-year-old man presented with unintentional weight loss and early satiety for 3 months and was found to have gastric adenocarcinoma after diagnostic testing. Further imaging demonstrated prostate enlargement and diffuse bony involvement, culminating in the diagnosis of a second primary tumor, prostate adenocarcinoma. A workup of gastric adenocarcinoma revealed metastasis to aortic-pulmonary (level 5) lymph nodes. Gastric outlet obstruction was treated with open gastrojejunostomy. Metastatic prostate cancer was treated with hormonal therapy.
Double primary tumors are rare occurrences and patient care should be optimized using an interdisciplinary care team. Treatment aims to mitigate disease progression, and is influenced by tumor type, anatomical location, and criteria for resectability.
Both gastric and prostate cancer pose significant challenges in both diagnosis and treatment, largely due to its often-asymptomatic nature in early stages and the complexity of its progression.
胃癌是隐匿性恶性肿瘤,通常在晚期才被诊断出来。同样,前列腺癌患者即使发生广泛转移也可能没有症状表现。这两种恶性肿瘤的隐匿性凸显了实施适当筛查方案以实现早期发现、及时治疗并改善患者预后的重要性。
一名66岁男性因3个月来非故意体重减轻和早饱就诊,诊断性检查后发现患有胃腺癌。进一步影像学检查显示前列腺增大和弥漫性骨受累,最终诊断为第二原发性肿瘤——前列腺腺癌。胃腺癌检查发现已转移至主动脉-肺(5区)淋巴结。通过开放式胃空肠吻合术治疗胃出口梗阻。转移性前列腺癌采用激素疗法治疗。
双原发性肿瘤很少见,应通过跨学科护理团队优化患者护理。治疗旨在减轻疾病进展,并受肿瘤类型、解剖位置和可切除性标准的影响。
胃癌和前列腺癌在诊断和治疗方面都带来了重大挑战,这主要是由于其早期通常无症状的特性及其进展的复杂性。