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优化前颅底脑膜瘤的手术治疗:成像方式、关键手术考量及风险缓解策略。

Optimizing Surgical Management of Anterior Skull Base Meningiomas: Imaging Modalities, Key Surgical Considerations, and Risk Mitigation Strategies.

作者信息

Ungureanu Gheorghe, Serban Larisa-Nicoleta, Florian Stefan-Ioan

机构信息

Department of Neurosciences, "Iuliu Hatieganu" University of Medicine and Pharmacy Cluj, 400347 Cluj-Napoca, Romania.

出版信息

Cancers (Basel). 2025 Mar 14;17(6):987. doi: 10.3390/cancers17060987.

Abstract

Skull base meningiomas present considerable challenges in surgical management due to their proximity to critical neurovascular structures. Anterior skull base meningiomas encompass olfactory groove, supra- and parasellar, anterior sphenoid ridge, cavernous sinus, and spheno-orbital tumors. The success of surgical resection and the likelihood of complications are influenced by several key factors, including the presence of an intact arachnoid plane, tumor size and consistency, peritumoral brain edema, cranial nerve involvement, vascular encasement, and invasion of critical areas such as the optic canal or cavernous sinus. These factors not only affect the feasibility of gross total resection but also play a pivotal role in determining functional outcomes and postoperative recovery. With the vast array of imaging modalities available, selecting the most appropriate investigations to assess these parameters and tailoring surgical strategies accordingly remain complex tasks. This review examines the critical surgical parameters, identifies the most effective imaging modalities for evaluating each, and provides key insights into how this analysis can guide surgical decision-making, mitigate risks, and minimize complications.

摘要

由于颅底脑膜瘤靠近关键的神经血管结构,其手术治疗面临着巨大挑战。前颅底脑膜瘤包括嗅沟、鞍上和鞍旁、前蝶骨嵴、海绵窦以及蝶眶肿瘤。手术切除的成功率和并发症的发生率受几个关键因素影响,包括蛛网膜平面是否完整、肿瘤大小和质地、瘤周脑水肿、脑神经受累情况、血管包绕以及对视神经管或海绵窦等关键区域的侵犯。这些因素不仅影响全切的可行性,还在决定功能预后和术后恢复方面起着关键作用。鉴于现有大量的成像方式,选择最合适的检查来评估这些参数并据此制定手术策略仍然是复杂的任务。本综述探讨了关键的手术参数,确定了评估每个参数最有效的成像方式,并提供了关于这种分析如何指导手术决策、降低风险和减少并发症的关键见解。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/746c/11940831/36b6a28f71d3/cancers-17-00987-g001.jpg

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