维生素D减少早期妊娠丢失：血清1,25-(OH)D调节与流产风险分析
Reducing early pregnancy loss with vitamin D: an analysis of serum 1,25-(OH)D modulation and miscarriage risk.
作者信息
Zhao Qian, Wang Liangying, Xiang Hongqin, Qiu Luling
机构信息
Department of Obstetrics and Gynecology in Hangzhou First People's Hospital Tonglu Hospital in Zhejiang Province, Hangzhou, No. 899 Meilin Road, Chengnan Street, Tonglu, Hangzhou 311500, Zhejiang Province, China.
出版信息
J Clin Biochem Nutr. 2025 Mar;76(2):164-178. doi: 10.3164/jcbn.24-147. Epub 2024 Oct 29.
This case-control study of 124 early-pregnant women found that daily supplementation with 400 IU of vitamin D significantly increased serum 1,25-(OH)D levels and was associated with a lower incidence of threatened miscarriage. The study suggests that vitamin D supplementation could reduce the risk of early miscarriage and improve pregnancy outcomes by modulating immune responses and hormonal stability.
这项针对124名早孕女性的病例对照研究发现，每日补充400国际单位的维生素D可显著提高血清1,25-(OH)D水平，并与先兆流产发生率较低相关。该研究表明，补充维生素D可通过调节免疫反应和激素稳定性来降低早期流产风险并改善妊娠结局。
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