Alio Jorge, Sanginabadi Azad, Hojabr Amir Theodore, Jafari Behzad
Division of Ophthalmology, Universidad Miguel Hernández, Alicante, Spain.
Vissum Alicante, Spain.
Am J Ophthalmol Case Rep. 2025 Mar 7;38:102297. doi: 10.1016/j.ajoc.2025.102297. eCollection 2025 Jun.
To assess the visual performance and complications of Femtosecond laser-assisted keratopigmentation for pure cosmetic purposes in a large consecutive series of cases.
This prospective study included 166 eyes that underwent pure keratopigmentation between 2021 and 2023 by one expert surgeon. Demographic data, preoperative examination findings, postoperative outcomes, and complications were collected and analyzed. Data were collected on preoperative and postoperative visual acuity, refraction, intraocular pressure, light sensitivity, endothelial cell count, visual field, and aberrometry. Preoperative and postoperative values were compared to determine any changes. There was no statistically significant difference (p > 0.05) in visual acuity, Mean deviation(MD) and IOP at 12 months after surgery. The presence of horizontal and vertical coma and trefoil aberrations, as well as spherical and HOA (Higher Order Aberration) errors, does not have statistically significant meaning. The mean endothelial cell count decreased from 2393.29 ± 123.69 cells/mm^2 preoperatively to 2308.58 ± 126.64 cells/mm^2 postoperatively. The contrast sensitivity has decreased across all spatial frequencies for mesopic conditions, and the decreases at 1.5 Cycles Pre Degree (CPD) and 18 CPD for photopic conditions were statistically significant. However, it still remains within the normal range.
Pure cosmetic keratopigmentation seems to be a safe and effective surgical technique for improving the cosmetic appearance of the eyes. The technique showed no significant impact on visual acuity, intraocular pressure, visual field. However, slight decreases in contrast sensitivity and endothelial cell count were observed, which should be considered when discussing potential risks and benefits with patients.
在一系列连续的大量病例中，评估飞秒激光辅助角膜色素沉着术用于单纯美容目的时的视觉性能和并发症。
这项前瞻性研究纳入了166只眼睛，这些眼睛在2021年至2023年间由一位专家外科医生进行了单纯角膜色素沉着术。收集并分析了人口统计学数据、术前检查结果、术后结局和并发症。收集了术前和术后的视力、屈光、眼压、光敏感度、内皮细胞计数、视野和像差测量数据。比较术前和术后的值以确定是否有任何变化。术后12个月时，视力、平均偏差（MD）和眼压无统计学显著差异（p>0.05）。水平和垂直彗差及三叶草像差的存在，以及球差和高阶像差（HOA）误差均无统计学显著意义。平均内皮细胞计数从术前的2393.29±123.69个细胞/mm²降至术后的2308.58±126.64个细胞/mm²。在中暗视觉条件下，所有空间频率的对比敏感度均下降；在明视觉条件下，1.5周/度（CPD）和18 CPD时的下降具有统计学显著性。然而，其仍处于正常范围内。
单纯美容性角膜色素沉着术似乎是一种安全有效的改善眼部外观的手术技术。该技术对视力、眼压、视野无显著影响。然而，观察到对比敏感度和内皮细胞计数略有下降，在与患者讨论潜在风险和益处时应予以考虑。
