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持续性耐甲氧西林金黄色葡萄球菌菌血症患者使用特拉万星治疗失败

Clinical Telavancin Failure in Persistent Methicillin-Resistant Staphylococcus aureus Bacteremia.

作者信息

Dao Kevin T, D'Assumpcao Carlos, Sharma Rupam, Singh Chandpreet, Kuran Rasha, Heidari Arash

机构信息

Internal Medicine, UCLA-Kern Medical, Bakersfield, USA.

Infectious Diseases, UCLA-Kern Medical, Bakersfield, USA.

出版信息

Cureus. 2025 Feb 24;17(2):e79588. doi: 10.7759/cureus.79588. eCollection 2025 Feb.

Abstract

Telavancin is a fairly novel antibiotic derived from vancomycin developed to combat the constant evolutionary war against bacteria. It has achieved high clinical success in its role in treating Gram-positive organisms, although like in the case of any other antibiotics, failure can arise. The purpose of this article is to describe a case in which telavancin clinically failed in treating persistent methicillin-resistant (MRSA) bacteremia in a patient while describing the cause that led to telavancin failure.

摘要

特拉万星是一种相当新颖的抗生素,由万古霉素衍生而来,用于对抗与细菌持续不断的进化之战。它在治疗革兰氏阳性菌方面取得了很高的临床成功率,尽管与任何其他抗生素一样,也可能出现治疗失败的情况。本文旨在描述一例特拉万星在临床上治疗一名患者的持续性耐甲氧西林金黄色葡萄球菌(MRSA)菌血症失败的病例,并阐述导致特拉万星治疗失败的原因。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8644/11948889/976ebaaef190/cureus-0017-00000079588-i01.jpg

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