Öner Fatih, Kurt Nezahat, Üçüncü Harun
Kastamonu University Faculty of Medicine, Department of Otorhinolaryngology, Kastamonu, Türkiye.
Erzincan Binali Yıldırım University Faculty of Medicine, Department of Medical Biochemistry, Erzincan, Türkiye.
Turk Arch Otorhinolaryngol. 2025 Mar 28;62(4):161-167. doi: 10.4274/tao.2024.2024-9-4.
Heavy metal exposure has recently become a problem due to the increasing environmental pollution as urbanization expands. This prospective cross-sectional study was conducted to compare levels of heavy metals in the nasal concha of the patients living in urban and rural who underwent partial inferior concha resection.
Sixty-seven patients were divided into two groups: 38 rural patients and 29 urban patients. Partial inferior turbinate resection was performed in these patients with turbinate hypertrophy, and these tissues were examined for heavy metal levels. Lead (Pb), cadmium (Cd), zinc (Zn), copper (Cu), and manganese (Mn) levels were measured in inferior nasal concha by inductively coupled plasma- optical emission spectrometry.
The levels of Cu (0.24±0.048 vs. 0.06±0.019 μg/g) and Zn (3.29±0.69 vs. 0.44±0.14 μg/g) of the rural patients were significantly higher compared to urban patients (p<0.001). There was no significant difference in the Cd level between groups. Pb (0.024±0.009 vs. 0.008±0.0002 μg/g) and Mn (0.273±0.01 vs. 0.174±0.05 μg/g) levels of urban patients were significantly higher than rural patients (p<0.001). Significance was considered at p<0.05.
Heavy metals accumulate in the nasal concha at different rates in rural and urban areas. In pathologies with unclear pathophysiology and potential for heavy metal accumulation, such as air pollution, it may be helpful to indicate the presence of heavy metals in the nasal turbinate's and measure their amounts for diagnostic purposes.
随着城市化进程的加快，环境污染日益严重，重金属暴露已成为一个问题。本前瞻性横断面研究旨在比较接受部分下鼻甲切除术的城乡患者鼻甲中重金属的含量水平。
67例患者分为两组：38例农村患者和29例城市患者。对这些鼻甲肥大的患者进行部分下鼻甲切除术，并对切除组织进行重金属含量检测。采用电感耦合等离子体发射光谱法测定下鼻甲中铅（Pb）、镉（Cd）、锌（Zn）、铜（Cu）和锰（Mn）的含量。
农村患者的铜（0.24±0.048 vs. 0.06±0.019μg/g）和锌（3.29±0.69 vs. 0.44±0.14μg/g）含量水平显著高于城市患者（p<0.001）。两组间镉含量无显著差异。城市患者的铅（0.024±0.009 vs. 0.008±0.0002μg/g）和锰（0.273±0.01 vs. 0.174±0.05μg/g）含量水平显著高于农村患者（p<0.001）。p<0.05被认为具有统计学意义。
重金属在城乡地区的鼻甲中以不同速率蓄积。在病理生理学不明确且存在重金属蓄积可能性的疾病中，如空气污染，指出鼻甲中重金属的存在并测量其含量可能有助于诊断。
