Repo R U, Shimizu H, Occhionorelli J, Margolian S
Arch Orthop Trauma Surg (1978). 1985;103(6):367-70. doi: 10.1007/BF00435442.
The purpose of this study was to compare the rates of bone growth with four different surfaces of cobalt-chrome implants. Two of the implant surfaces were coated by a glass-ceramic of our own composition. One coating was porous. No enhancement of bone ingrowth was found in the glass-ceramic implants. The degree of metal ion contamination was also assessed, and significant, potentially harmful contamination by metal ions was found in the glass-ceramic. This study points out the need for better techniques of coating metal with glass-ceramic to avoid potential carcinogenic effects.
本研究的目的是比较钴铬合金植入物四种不同表面的骨生长速率。其中两种植入物表面涂覆了我们自己配制的微晶玻璃。一种涂层是多孔的。在微晶玻璃植入物中未发现骨长入增强。还评估了金属离子污染程度,发现微晶玻璃中存在显著的、潜在有害的金属离子污染。本研究指出需要更好的用微晶玻璃涂覆金属的技术,以避免潜在的致癌作用。