Piotrowski G, Hench L L, Allen W C, Miller G J
J Biomed Mater Res. 1975 Jul;9(4):47-61. doi: 10.1002/jbm.820090408.
A series of squirrel monkeys received segmental femoral replacements in a study of the strength of the interface developed between the implant and bone. Implants were either made completely of bioglass-ceramic, or 316L stainless steel with a flame-sprayed coating of bioglass. Fracture torque, energy at fracture, and shear stress at failure were compared to values obtained from a control group of pairs of tibias. Femurs containing bulk bioglass-ceramic implants showed about a 25% difference in strength compared to the opposite bone, while femurs containing flame-sprayed implants exhibited extremely low structural strength. While the strength of the metal-glass bond was very low (less than 500 kgf/cm2), the bone-bioglass bond was found to be at least as strong as the bioglass-ceramic, and at least 3/4 as strong as the host bone.
在一项关于植入物与骨骼之间形成的界面强度的研究中，对一系列松鼠猴进行了股骨节段置换。植入物要么完全由生物玻璃陶瓷制成，要么是带有生物玻璃火焰喷涂涂层的316L不锈钢。将骨折扭矩、骨折能量和失效时的剪应力与从成对胫骨对照组获得的值进行比较。与对侧骨骼相比，含有块状生物玻璃陶瓷植入物的股骨在强度上显示出约25%的差异，而含有火焰喷涂植入物的股骨表现出极低的结构强度。虽然金属-玻璃结合强度非常低（小于500千克力/平方厘米），但发现骨-生物玻璃结合至少与生物玻璃陶瓷一样强，且至少是宿主骨强度的3/4。
