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COVID-19 住院后的患者身体状况和功能后遗症:一项横断面观察性研究。

Patient physical condition and functional sequelae following hospitalization with COVID-19: A cross-sectional observational study.

作者信息

Ángel García Daniel, Calvo Muñoz Inmaculada, Martínez Nicolás Ismael, Salmeri Bianca

机构信息

Faculty of Physiotherapy, Occupational Therapy and Podiatry, UCAM Catholic University of Murcia, Murcia, Spain.

Fundación para la Formación e Investigación Sanitarias de la Región de Murcia, Instituto Murciano de Investigación Biosanitaria Pascual Parrilla, Murcia, Spain.

出版信息

Medicine (Baltimore). 2025 Mar 28;104(13):e41948. doi: 10.1097/MD.0000000000041948.

Abstract

After hospitalization caused by COVID-19, a high prevalence of physical deterioration has been observed, hence the importance of having tests to evaluate the functional status of patients and to be able to perform a partition and subsequent referral to the physiotherapy service. This cross-sectional observational study describes the physical status according to the short physical performance battery (SPPB) of patients admitted to the hospital setting for COVID-19 and to identify variables potentially related to this outcome. Thirty-six patients admitted to the hospital setting for COVID-19 in the first wave living in the community. Patients were evaluated with the SPPB, strength test, the International Physical Activity Questionnaire, the 1-minute sit-to stand, spirometry, the Barthel index, the Hospital Anxiety and Depression Scale, and other patient-related data were collected. We performed bivariate and regression analyses. A linear regression was fitted, having SPPB as a dependent variable to ascertain the impact of intensive care unit (ICU) admission on physical performance. Five variables were related to SPPB. There was a significant relationship between admission to the ICU and having a heart disease (P = .015), the level of physical activity (P = .049), number of years smoking (P = .029) and days of hospitalization (P = .005). A total of 22.22% of analyzed patients suffered frailty. SPPB is related to altered respiratory pattern, quadriceps strength, 1-minute sit-to-stand and FEV1, Barthel score, days of hospitalization and FEV/FVC ratio. Lack of association between ICU stay, age or sex with SPPB results differs from the results of other studies.

摘要

在因新型冠状病毒肺炎(COVID-19)住院后,已观察到身体机能衰退的高发生率,因此进行检测以评估患者的功能状态并能够进行分类以及随后转诊至物理治疗服务非常重要。这项横断面观察性研究描述了因COVID-19入住医院的患者根据简短体能状况量表(SPPB)得出的身体状况,并确定与该结果潜在相关的变量。36名在第一波疫情中居住在社区且因COVID-19入住医院的患者。对患者进行了SPPB评估、力量测试、国际体力活动问卷、1分钟坐立试验、肺活量测定、Barthel指数、医院焦虑抑郁量表评估,并收集了其他与患者相关的数据。我们进行了双变量分析和回归分析。以SPPB作为因变量拟合线性回归,以确定入住重症监护病房(ICU)对身体机能的影响。有五个变量与SPPB相关。入住ICU与患有心脏病(P = 0.015)、体力活动水平(P = 0.049)、吸烟年数(P = 0.029)和住院天数(P = 0.005)之间存在显著关系。总共22.22%的分析患者存在身体虚弱。SPPB与呼吸模式改变、股四头肌力量、1分钟坐立试验和第1秒用力呼气量(FEV1)、Barthel评分、住院天数以及FEV/用力肺活量(FVC)比值相关。ICU住院时间、年龄或性别与SPPB结果之间缺乏关联,这与其他研究结果不同。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0fba/11957633/753805964bd2/medi-104-e41948-g001.jpg

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