Awad Abanoub, Theerman Isaac, Beckermann Jason
Mayo Clinic Health System, Eau Claire, WI 54703, USA.
Mayo Clinic Health System, Eau Claire, WI 54703, USA.
Int J Surg Case Rep. 2025 Apr;129:111203. doi: 10.1016/j.ijscr.2025.111203. Epub 2025 Mar 25.
Gastrointestinal stromal tumors (GISTs) are rare mesenchymal tumors that originate from interstitial cells of Cajal. They most commonly occur in the stomach, followed by the small bowel. Jejunal GISTs are particularly rare and often present with nonspecific symptoms. However, they can also present with gastrointestinal bleeding and intussusception, complicating diagnosis and treatment.
We report a case of a 58-year-old male who presented with melena and anemia due to a bleeding intussuscepting jejunal gastrointestinal stromal tumor (GIST). The patient underwent jejunal resection and anastomosis. The postoperative course was uncomplicated, and the patient made a full recovery.
Gastrointestinal stromal tumors (GISTs) can present with melena and acute or chronic anemia due to gastrointestinal bleeding. The bleeding typically results from ulceration or erosion of blood vessels within the tumor. The diagnosis is often challenging, as the symptoms are nonspecific. Imaging techniques such as CT scans are essential for identifying the tumor, and surgical resection is the primary treatment, providing favorable outcomes for localized, low-risk cases.
Gastrointestinal stromal tumors (GISTs), although rare, should be considered in the differential diagnosis of patients presenting with gastrointestinal bleeding and anemia.
胃肠道间质瘤（GISTs）是起源于 Cajal 间质细胞的罕见间叶组织肿瘤。它们最常发生于胃部，其次是小肠。空肠 GISTs 尤为罕见，且常表现为非特异性症状。然而，它们也可能出现胃肠道出血和肠套叠，使诊断和治疗复杂化。
我们报告一例 58 岁男性患者，因出血性套叠性空肠胃肠道间质瘤（GIST）出现黑便和贫血。患者接受了空肠切除及吻合术。术后过程顺利，患者完全康复。
胃肠道间质瘤（GISTs）可因胃肠道出血而出现黑便以及急性或慢性贫血。出血通常是由于肿瘤内血管的溃疡或糜烂所致。由于症状不具特异性，诊断往往具有挑战性。诸如 CT 扫描等影像学技术对于识别肿瘤至关重要，手术切除是主要治疗方法，对于局限性、低风险病例可取得良好疗效。
胃肠道间质瘤（GISTs）虽罕见，但在出现胃肠道出血和贫血的患者鉴别诊断中应予以考虑。
