Sapin M R, Kharin G M
Arkh Anat Gistol Embriol. 1985 Apr;88(4):65-9.
By means of morphometrical and histochemical methods serial topographic sections of the spleen have been studied in 23 Papio hamadryas of five age groups: fetuses, newborns, 1.5-2 years of age, mature and old animals. The peculiarities of morphogenesis and age histology of the monkey spleen have been followed and their similarity with changes of the organ in the human ontogenesis has been compared. Owing to the analysis of the structural components and the cellular composition relations, it is possible to conclude that in the fetuses the histological structure of the spleen is not completed, the maximal cytopoetic activity of the organ is observed in 1.5-2-year-old animals and involutionary changes begin in mature period. Possible functional peculiarities of the spleen are considered during various age periods.
通过形态计量学和组织化学方法，对23只来自五个年龄组的阿拉伯狒狒的脾脏连续断层切片进行了研究，这五个年龄组分别为：胎儿、新生儿、1.5 - 2岁、成年和老年动物。追踪了猴脾脏形态发生和年龄组织学的特点，并将其与人类个体发育中器官的变化进行了比较。通过对结构成分和细胞组成关系的分析，可以得出结论：在胎儿期，脾脏的组织结构尚未发育完全；在1.5 - 2岁的动物中观察到该器官的最大细胞生成活性；退化性变化始于成年期。还考虑了脾脏在不同年龄阶段可能具有的功能特点。
