Paulson G W, Martin E W, Mojzisik C, Carey L C
Arch Neurol. 1985 Jul;42(7):675-7. doi: 10.1001/archneur.1985.04060070065017.
Six patients who had gastric reduction for morbid obesity suffered severe complex neurologic disturbances that included confusion and inappropriate behavior. All were profoundly weak or paraplegic, and recovery was delayed and incomplete. Encephalopathy was documented by EEG and neurologic examination. The cause is uncertain. Acute catabolism of lipid may predispose to damage of the nervous system, but relative vitamin deficiency is a more obvious and treatable explanation.
6例因病态肥胖接受胃减容手术的患者出现了严重的复杂神经功能障碍,包括意识模糊和行为异常。所有患者均极度虚弱或截瘫,恢复延迟且不完全。脑电图和神经系统检查证实存在脑病。病因尚不确定。脂质的急性分解代谢可能易导致神经系统损伤,但相对维生素缺乏是一个更明显且可治疗的解释。