Seehra H, MacDermott N, Lascelles R G, Taylor T V
Department of Surgery, Manchester Royal Infirmary, Manchester, UK.
BMJ. 1996 Feb 17;312(7028):434. doi: 10.1136/bmj.312.7028.434.
Thiamine deficiency is known to lead to certain neurological sequelae including Wernicke- Korsakoff encephalopathy. Signs attributable to this condition include ataxia, ophthalmoplegia, nystagmus, and mental confusion. Recognised predisposing conditions include alcoholism gastric carcinoma, pyloric obstruction, hyperemesis gravidarum, and prolonged intravenous feeding. We have recently encountered two cases of Wernicke's encephalopathy after vertical banded gastroplasty for morbid obesity . Other neurological sequelae are recognised after vertical banded gastroplasty, including Guillain-Barre syndrome, psychosis, and pseudoathetosis, but the causes are multifactorial.
已知硫胺素缺乏会导致某些神经后遗症,包括韦尼克-科萨科夫脑病。该病症的体征包括共济失调、眼肌麻痹、眼球震颤和精神错乱。公认的诱发因素包括酗酒、胃癌、幽门梗阻、妊娠剧吐和长期静脉营养。我们最近遇到了两例因病态肥胖接受垂直捆扎胃成形术后发生韦尼克脑病的病例。垂直捆扎胃成形术后还可出现其他神经后遗症,包括吉兰-巴雷综合征、精神病和假手足徐动症,但其病因是多因素的。